SML3326

WSP5

≥90% (HPLC)

• Synonym(e): 1,1′-(3-Oxospiro[isobenzofuran-1(3H),9′-[9H]xanthene]-3′,6′-diyl) bis[2-(2-pyridinyldithio)benzoate], Benzoic acid, 2-(2-pyridinyldithio)-, 1,1′-(3-oxospiro[isobenzofuran-1(3H),9′-[9H]xanthene]-3′,6′-diyl) ester, H2S fluorescent probe WSP5, Hydrogen sulfide fluorescent probe WSP-5, WSP-5
• Empirische Formel (Hill-System): C₄₄H₂₆N₂O₇S₄
• CAS-Nummer: 1593024-78-2
• Molekulargewicht: 822.95
• UNSPSC-Code: 12352200
• NACRES: NA.21

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥90% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear (Warmed)
• Lagertemp.: 2-8°C
• SMILES String: O=C(C1=C(SSC2=NC=CC=C2)C=CC=C1)OC3=CC=C4C(OC5=CC(OC(C6=C(SSC7=NC=CC=C7)C=CC=C6)=O)=CC=C5C48OC(C9=C8C=CC=C9)=O)=C3
• InChI: 1S/C44H26N2O7S4/c47-41(30-12-2-5-15-37(30)54-56-39-17-7-9-23-45-39)50-27-19-21-33-35(25-27)52-36-26-28(20-22-34(36)44(33)32-14-4-1-11-29(32)43(49)53-44)51-42(48)31-13-3-6-16-38(31)55-57-40-18-8-10-24-46-40/h1-26H
• InChIKey: DSMMZTASSIAQPQ-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

Cell-permeable, highly selective, turn-on fluorescent probe for hydrogen sulfide (H2S)

WSP5 is a cell-permeable fluoresceinyl pyridine disulfide compound that acts as a highly selective, fast- and time-dependent nucleophilic substitution–cyclization-based H2S sensitive fluorescent turn-on live cells probe (60-fold; ƛex = 502 nm & ƛem = 525 nm; ɸ = 0.20 & a detection limit = 47 nM). WSP5 is reported to function over biological pH ranges and insensitive towards bio-thiols, various reactive sulfur species and esterases.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable