SML0289

Bromfenac sodium

≥98% (HPLC)

• Synonym(e): 2-Amino-3-(4-bromobenzoyl)benzeneacetic acid sodium salt
• Empirische Formel (Hill-System): C₁₅H₁₁BrNNaO₃
• CAS-Nummer: 91714-93-1
• Molekulargewicht: 356.15
• MDL-Nummer: MFCD03701673
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825297
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Lagerbedingungen: desiccated
• Farbe: faintly yellow to dark yellow
• Löslichkeit: H₂O: ≥5 mg/mL
• Lagertemp.: 2-8°C
• SMILES String: [Na+].Nc1c(CC([O-])=O)cccc1C(=O)c2ccc(Br)cc2
• InChI: 1S/C15H12BrNO3.Na/c16-11-6-4-9(5-7-11)15(20)12-3-1-2-10(14(12)17)8-13(18)19;/h1-7H,8,17H2,(H,18,19);/q;+1/p-1
• InChIKey: HZFGMQJYAFHESD-UHFFFAOYSA-M
• Angaben zum Gen: human ... PTGS1(5742) , PTGS2(5743)

Beschreibung

Anwendung

Bromfenac sodium has been used:

• to study its ability to bind to melanin
• in the synthesis of bromfenac indolinone standard
• to analyze its permeability in porcine conjunctiva

Biochem./physiol. Wirkung

Bromfenac exhibits antipyretic and prostaglandin synthetase inhibiting properties. It has therapeutic properties against the reduction of ocular pain and inflammation in postoperative cataract patients. Bromfenac acts as an effective agent against allergic conjunctivitis. It has the potential to treat acute muscle pain, osteoarthritis, and rheumatoid arthritis.

Bromfenac is a nonsteroidal anti inflammatory drug (NSAID) that inhibits both COX1 and COX2. It is used as an opthalmic analgesic.

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H301
• P-Sätze: P264 - P270 - P301 + P310 - P405 - P501
• Gefahreneinstufungen: Acute Tox. 3 Oral
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable