SML0248

Zolmitriptan

≥98% (HPLC)

• Synonym(e): (4S)-4-((3-(2-(Dimethylamino)-ethyl)-1H-indol-5-yl)-methyl)-2-oxazolidinon, (S)-4-((3-(2-(Dimethylamino)-ethyl)-indol-5-yl)-methyl)-2-oxazolidinon
• Empirische Formel (Hill-System): C₁₆H₂₁N₃O₂
• CAS-Nummer: 139264-17-8
• Molekulargewicht: 287.36
• MDL-Nummer: MFCD00871503
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825258
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Optische Aktivität: [α]/D -3 to -8°, c = 1 in methanol
• Farbe: white to beige
• Löslichkeit: DMSO: ≥5 mg/mL
• Lagertemp.: 2-8°C
• SMILES String: CN(C)CCc1c[nH]c2ccc(C[C@H]3COC(=O)N3)cc12
• InChI: 1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1
• InChIKey: ULSDMUVEXKOYBU-ZDUSSCGKSA-N
• Angaben zum Gen: human ... HTR1B(3351) , HTR1D(3352)

Beschreibung

Anwendung

Zolmitriptan has been used as a 5-hydroxytryptamine receptor 1B (5-HT_1B/D) activator to treat grafts to study its effects on the morphology of the ectopic eye.

Zolmitriptan has been used to induce hyper-innervation of transplants.

Biochem./physiol. Wirkung

Zolmitriptan is a selective serotonin receptor agonist of the 5HT1B and 5HT1D subtypes, both centrally and peripherally. It has been used clinically for the acute treatment of migraine attacks with or without aura and cluster headaches.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable