SML0096

Cinnabarinic Acid

≥98% (HPLC)

• Synonym(e): 2-amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic acid, Cinnabaric acid
• Empirische Formel (Hill-System): C₁₄H₈N₂O₆
• CAS-Nummer: 606-59-7
• Molekulargewicht: 300.22
• MDL-Nummer: MFCD18379297
• UNSPSC-Code: 12352106
• PubChem Substanz-ID: 329825154
• NACRES: NA.25

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Lagerbedingungen: desiccated
• Farbe: red to very dark red
• Löslichkeit: DMSO: ≥4 mg/mL
• Lagertemp.: 2-8°C
• SMILES String: NC1=C(C(O)=O)C2=Nc3c(OC2=CC1=O)cccc3C(O)=O
• InChI: 1S/C14H8N2O6/c15-10-6(17)4-8-12(9(10)14(20)21)16-11-5(13(18)19)2-1-3-7(11)22-8/h1-4H,15H2,(H,18,19)(H,20,21)
• InChIKey: FSBKJYLVDRVPTK-UHFFFAOYSA-N

Beschreibung

Anwendung

Cinnabarinic acid may be used in studies of the functions of components of the kynurenine metabolic pathway. It may be used to study it role as a metabotropic glutamate receptor (mGlu4R-specific) agonist.

Biochem./physiol. Wirkung

Caspase Inducer; mGlu4R agonist
Cinnabarinic acid (CA) connects between initiation of the kynurenine pathway and immune tolerance that is used to prevent neuroinflammation.

Cinnabarinic acid is a kynurenine pathway metabolite of tryptophan, produced by the oxidation of 3-Hydroxyanthranilic acid. Cinnabarinic acid leads to loss of mitochondrial respiration and apoptosis, and has also been shown to be an mGlu4R-specific agonist.

Leistungsmerkmale und Vorteile

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Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable