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Merck

SMB01027

Sigma-Aldrich

Pomiferin

≥90% (LC/MS-ELSD)

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About This Item

Empirische Formel (Hill-System):
C25H24O6
CAS-Nummer:
Molekulargewicht:
420.45
MDL-Nummer:
UNSPSC-Code:
12352205
NACRES:
NA.25

Biologische Quelle

plant

Assay

≥90% (LC/MS-ELSD)

Form

solid

Mol-Gew.

420.45

Anwendung(en)

metabolomics
vitamins, nutraceuticals, and natural products

Lagertemp.

−20°C

InChI

1S/C25H24O6/c1-13(2)5-7-15-21(28)20-22(29)17(14-6-8-18(26)19(27)11-14)12-30-24(20)16-9-10-25(3,4)31-23(15)16/h5-6,8-12,26-28H,7H2,1-4H3

InChIKey

GHCZYXUOYFOXIP-UHFFFAOYSA-N

Allgemeine Beschreibung

Pomiferin is a prenylated flavonoid and a bioactive natural compound commonly derived from plants such as Citrus aurantium, Derris montana, Maclura pomifera, and Acacia horrida. Current research indicates that this metabolite is an inhibitor and may possess diverse biological activities, including antimicrobial, anticancer, antioxidant, anti-inflammatory, and neuroprotective properties.

Anwendung

Pomiferin is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Biochem./physiol. Wirkung

Pomiferin acts as an potential inhibitor of HDAC, with an IC50 of 1.05 μM, and also potently inhibits mTOR (IC50, 6.2 μM). Pomiferin shows cytotoxic effects on human tumor cell lines. Pomiferin also increases SOD activities and total antioxidative capacity, and decreases malondialdehyde in rats.

Leistungsmerkmale und Vorteile

  • Suitable for Biochemical and Biomedical research
  • Versatile and adaptable for wide variety of laboratory and research applications

Sonstige Hinweise

For additional information on our range of Biochemicals, please complete this form.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Raymond Yang et al.
Journal of agricultural and food chemistry, 59(24), 13328-13336 (2011-11-18)
Pomiferin and osajin are prenylated isoflavones from Osage orange fruit that both have potent antioxidant activity in a variety of assays. Pomiferin, in particular, has strong activity against the superoxide anion in a photochemiluminescence (PCL) assay system. In vitro, pomiferin
Il Hong Son et al.
Bioorganic & medicinal chemistry letters, 17(17), 4753-4755 (2007-07-31)
The major constituents from the fruits of Maclura pomifera are the prenylated isoflavones, osajin (1) and pomiferin (2). Their structures were elucidated using NMR spectroscopic techniques and mass spectrometric analysis. Compound 2 showed potential inhibitory activity in histone deacetylase (HDAC)

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