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Merck

SAB5600251

Sigma-Aldrich

Anti-N6-Methyladenosine (m6A) antibody, Rabbit monoclonal

recombinant, expressed in HEK 293 cells, clone RM362, purified immunoglobulin

Synonym(e):

m6A

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Rekombinant

expressed in HEK 293 cells

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

RM362, monoclonal
recombinant monoclonal

Form

buffered aqueous glycerol solution

Speziesreaktivität

vertebrates, human

Methode(n)

ELISA: 0.1-3 μg/mL
dot blot: 0.5-2 μg/mL
immunocytochemistry: 0.1— 3 μg/mL
immunoprecipitation (IP): .2-5 μg/mL (Methylated RNA)

Isotyp

IgG

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... METTL3(56339)

Spezifität

This antibody reacts to N6-Methyladenosine (m6A) in both RNA and DNA. No cross reactivity with non-methylated adenosine.

Immunogen

BSA-conjugated N6-Methyladenosine

Physikalische Form

Solution in phosphate buffered saline containing 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Fang Wang et al.
Chinese medicine, 18(1), 122-122 (2023-09-22)
Curdione is a sesquiterpene isolated from Curcumae Rhizoma that possesses high biological activity and extensive pharmacological effects. As a traditional Chinese medicine, Curcumae Rhizoma can inhibit the development of many types of cancer, especially colorectal cancer. However, the anti-colorectal mechanism
Shuai Ren et al.
Annals of translational medicine, 11(1), 15-15 (2023-02-11)
Keloid is a dermal fibrotic disease characterized by excessive proliferation of dermal fibroblasts and deposition of excessive collagen. N6-methyladenosine (m6A) plays a significant role in numerous physiological and pathological regulatory processes in the human body. Fat mass and obesity-associated protein
Yufan Ying et al.
Molecular cancer, 23(1), 79-79 (2024-04-25)
R-loops are prevalent three-stranded nucleic acid structures, comprising a DNA-RNA hybrid and a displaced single-stranded DNA, that frequently form during transcription and may be attributed to genomic stability and gene expression regulation. It was recently discovered that RNA modification contributes

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