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Merck

SAB4301137

Sigma-Aldrich

Anti-ACTIN antibody produced in rabbit

affinity isolated antibody

Synonym(e):

ACTB

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

42 kDa

Speziesreaktivität

plant

Konzentration

1 mg/mL

Methode(n)

western blot: 1:500-1:2000 (Cell Lysate)

Isotyp

IgG

Hinterlegungsnummer

NP_190236.1

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

Arabidopsis thaliana ... ACT12(823805)

Allgemeine Beschreibung

Actin/ actin β(ACTB) is encoded by the gene mapped to human chromosome 7p15-p12. In mammals, actin protein consists of six different isoforms encoded by separate genes. The four isoforms αskeletal-actin, αcardiac-actin, αsmooth-actin, and γ smooth-actin are expressed in skeletal, cardiac and smooth muscle. The other two isoforms, β cyto-actin and γ cyto-actin are ubiquitously expressed.

Spezifität

The antibody detects endogenous levels of total ACTIN protein.

Immunogen

Synthetic peptide corresponding to residues near the N terminal of Arabidopsis thaliana actin

Biochem./physiol. Wirkung

Actin plays a vital role in various cellular processes, such as cell division, migration, junction formation, chromatin remodeling, transcriptional regulation, vesicle trafficking, and cell shape regulation. Polymorphism in the smooth muscle α-actin (ACTA2) is associated with the development of thoracic aortic aneurysms and dissections.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1


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Die Dokumentenbibliothek aufrufen

Elizabeth Feldeverd et al.
Frontiers in plant science, 11, 610052-610052 (2021-01-16)
Plants adapt to heat via thermotolerance pathways in which the activation of protein folding chaperones is essential. In eukaryotes, protein disulfide isomerases (PDIs) facilitate the folding of nascent and misfolded proteins in the secretory pathway by catalyzing the formation and
Mutations in smooth muscle ?-actin (ACTA2) lead to thoracic aortic aneurysms and dissections.
Guo D C, et al.
Nature Genetics, 39(12), 1488-1488 (2007)
Dong Meng et al.
The Plant journal : for cell and molecular biology, 106(5), 1278-1297 (2021-03-19)
Calcineurin B-like (CBL)-interacting protein kinases (CIPKs) play a central role in Ca2+ signalling and promote drought tolerance in plants. The CIPK gene family in pigeon pea (Cajanus cajan L.), a major food crop affected by drought, has not previously been
Lucie Horakova et al.
Frontiers in physiology, 13, 1033130-1033130 (2023-01-27)
Ectodysplasin (Eda) plays important roles in both shaping the developing tooth and establishing the number of teeth within the tooth row. Sonic hedgehog (Shh) has been shown to act downstream of Eda and is involved in the initiation of tooth
Kimihito Saito et al.
Tissue barriers, 11(3), 2106113-2106113 (2022-07-28)
Lipolysis-stimulated lipoprotein receptor (LSR), a lipid metabolism-related factor localized in tricellular tight junctions (tTJs), plays an important role in maintaining the epithelial barrier. LSR is highly expressed in well-differentiated endometrial endometrioid carcinoma (EEC), and its expression decreases during malignancy. Angubindin-1

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