SAB2900202

Anti-CX3CR1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(e): beta chemokine receptor-like 1, chemokine c-x3-c receptor 1, cmkbrl1, cmkdr1, fkn receptor
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Speziesreaktivität: human
• Methode(n): immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
• UniProt-Hinterlegungsnummer: P49238
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... CX3CR1(1524)

Beschreibung

Allgemeine Beschreibung

C-X3-C motif chemokine receptor 1 (CX3CR1) is a transmembrane G-coupled chemokine receptor of its ligand, fractalkine. This receptor is expressed on epithelial cells, smooth muscle cells, microglia, monocytic cells and natural killer cells. The gene encoding CX3CR1 is localized on human chromosome 3p21.3 and has five exons.

Immunogen

Synthetic 19 amino acid peptide from 3rd extracellular domain of human CX3CR1. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Gibbon, Monkey (95%); Marmoset, Mouse, Panda (84%).

Biochem./physiol. Wirkung

C-X3-C motif chemokine receptor 1 (CX3CR1) may be linked to the development of macular degeneration. It also acts as a receptor aiding viral entry.

Leistungsmerkmale und Vorteile

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Physikalische Form

Solution in phosphate-buffered saline containing less than 0.1% sodium azide.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable