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Wichtige Dokumente

SAB2501105

Sigma-Aldrich

Anti-VPS29, C-Terminal antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(e):

Anti-DC15, Anti-DC7, Anti-DKFZp564F0223, Anti-FLJ20492, Anti-PEP11

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

goat

Qualitätsniveau

100

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Speziesreaktivität

canine, rat, human, mouse

Methode(n)

indirect ELISA: suitable
western blot: suitable

UniProt-Hinterlegungsnummer

Q9UBQ0

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... VPS29(51699)

Immunogen

Peptide with sequence C-DDVKVERIEYKKP from the C Terminus of the protein sequence according to NP_057310.1; NP_476528.1.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Yasir H Qureshi et al.
Cell reports, 38(3), 110262-110262 (2022-01-20)
Disruption of retromer-dependent endosomal trafficking is considered pathogenic in late-onset Alzheimer's disease (AD). Here, to investigate this disruption in the intact brain, we turn to a genetic mouse model where the retromer core protein VPS35 is depleted in hippocampal neurons
Eduardo J Pérez-Torres et al.
Proceedings of the National Academy of Sciences of the United States of America, 119(26), e2118755119-e2118755119 (2022-06-25)
Retromer is a heteropentameric complex that plays a specialized role in endosomal protein sorting and trafficking. Here, we report a reduction in the retromer proteins-vacuolar protein sorting 35 (VPS35), VPS26A, and VPS29-in patients with amyotrophic lateral sclerosis (ALS) and in
Sabrina Simoes et al.
Cell reports, 37(13), 110182-110182 (2021-12-30)
Whether and how the pathogenic disruptions in endosomal trafficking observed in Alzheimer's disease (AD) are linked to its anatomical vulnerability remain unknown. Here, we began addressing these questions by showing that neurons are enriched with a second retromer core, organized

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