SAB1306582

Anti-Ubiquitin antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• Synonym(e): Polyubiquitin-C, UBC, Ubiquitin
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: IgG fraction of antiserum
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: 77039 Da
• Speziesreaktivität: human
• Methode(n): immunofluorescence: 1:10-1:50; immunohistochemistry: 1:50-1:100; western blot: 1:1000
• UniProt-Hinterlegungsnummer: P0CG48
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... UBC(7316)

Beschreibung

Allgemeine Beschreibung

Ubiquitin, also known as ubiquitin C (UBC), is a globular protein, encoded by the gene mapped to human chromosome 12q24.31. The encoded protein consists of 76 amino acids.

Immunogen

a synthetic peptide between 36-66 amino acids of human Ubiquitin, which is in the Ubiquitin-like 1 domain

Anwendung

Anti-ubiquitin antibody produced in rabbit has been used in western blotting.

Biochem./physiol. Wirkung

Ubiquitin plays a major role in protein degradation. Ubiquitin-mediated degradation of regulatory proteins has been implicated in the regulation of various processes, such as cell-cycle progression, signal transduction, transcriptional regulation, receptor down-regulation and endocytosis. Aberrations in the ubiquitin-mediated pathways contribute to malignant transformation.

Physikalische Form

Supplied in PBS with 0.09% (W/V) sodium azide

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable