Direkt zum Inhalt
Merck
Alle Fotos(1)

Wichtige Dokumente

Gesamtdokumentation anzeigen

P1499

Sigma-Aldrich

Pterostilben

≥97% (HPLC), solid

Synonym(e):

Pterocarpus marsupium, 3,5-Dimethoxy-4′-hydroxystilbene, 4-[(1E)-2-(3,5-Dimethoxyphenyl)ethenyl]phenol

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(1)

About This Item

Empirische Formel (Hill-System):
C16H16O3
CAS-Nummer:
537-42-8
Molekulargewicht:
256.30
MDL-Nummer:
MFCD00238710
UNSPSC-Code:
12352200
PubChem Substanz-ID:
24724573
NACRES:
NA.77

Qualitätsniveau

100

Assay

≥97% (HPLC)

Form

solid

Lagerbedingungen

protect from light

Löslichkeit

DMSO: >20 mg/mL
H2O: insoluble

Lagertemp.

2-8°C

SMILES String

COc1cc(OC)cc(\C=C\c2ccc(O)cc2)c1

InChI

1S/C16H16O3/c1-18-15-9-13(10-16(11-15)19-2)4-3-12-5-7-14(17)8-6-12/h3-11,17H,1-2H3/b4-3+

InChIKey

VLEUZFDZJKSGMX-ONEGZZNKSA-N

Suchen Sie nach ähnlichen Produkten? Aufrufen Leitfaden zum Produktvergleich

Allgemeine Beschreibung

Pterostilbene (trans-3,5-dimethoxy-4-hydroxystilbene), an antioxidant is an analogue of resveratrol. It is present in blueberries, tree wood and some types of grapes.

Anwendung

Pterostilbene has been used:
  • to investigate its anti-oxidative stress activities and the involvement of the nuclear factor (erythroid-derived 2)-like 2 (Nrf2)-antioxidant response element (ARE) signaling pathway
  • to determine its effects on transcriptional activation of estrogen receptor-α (ERα) in hormone resistant breast cancer cells)
  • to study its effects on the cytotoxicity of 2-chloroethyl ethyl sulphide (CEES) in human epidermoid carcinoma cells (A-431) through MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide)viability assay

Biochem./physiol. Wirkung

Pterostilbene exhibits antineoplastic properties in some of the malignancies, hence it is considered as an active anticancer agent. It has the ability to stimulate apoptosis and block the viability of cell in estrogen-receptor positive and negative breast cancer cell lines.
Antioxidant, antiproliferative, apoptosis inducer, antihyperglycemic, antidiabetic.

Vorsicht

Air-sensitive

Piktogramme

CorrosionEnvironment
GHS05,GHS09

Signalwort

Danger

H-Sätze

H318,H411

Gefahreneinstufungen

Aquatic Chronic 2 - Eye Dam. 1

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Kunden haben sich ebenfalls angesehen

Slide 1 of 8

1 of 8

Triacetyl resveratrol ≥98% (HPLC)

Sigma-Aldrich

SML0032

Triacetyl resveratrol

Resveratrol analytical standard

Supelco

34092

Resveratrol

Validamycin A PESTANAL®, analytical standard

Supelco

32347

Validamycin A

4-Bromo-Resveratrol ≥98% (HPLC)

Sigma-Aldrich

SML1078

4-Bromo-Resveratrol

Polydatin ≥95% (HPLC)

Sigma-Aldrich

15721

Polydatin

Fenbendazol ≥98%

Sigma-Aldrich

F5396

Fenbendazol

D-Sorbit ≥98% (GC), BioReagent, suitable for cell culture, suitable for plant cell culture

Sigma-Aldrich

S3889

D-Sorbit

Betulinsäure ≥98% (HPLC)

Sigma-Aldrich

B8936

Betulinsäure

Hee Jeong Shin et al.
Molecules (Basel, Switzerland), 25(1) (2020-01-16)
Increasing studies have reported that cancer stem cells (CSCs) play critical roles in therapeutic resistance, recurrence, and metastasis of tumors, including cervical cancer. Pterostilbene, a dimethylated derivative of resveratrol, is a plant polyphenol compound with potential chemopreventive activity. However, the
Shih-Chun Yang et al.
Frontiers in microbiology, 8, 1103-1103 (2017-07-01)
Pterostilbene is a methoxylated derivative of resveratrol originated from natural sources. We investigated the antibacterial activity of pterostilbene against drug-resistant
Jaewon Chang et al.
Neurobiology of aging, 33(9), 2062-2071 (2011-10-11)
Recent studies have implicated resveratrol and pterostilbene, a resveratrol derivative, in the protection against age-related diseases including Alzheimer's disease (AD). However, the mechanism for the favorable effects of resveratrol in the brain remains unclear and information about direct cross-comparisons between
Victor Chia-Hsiang Lin et al.
Journal of agricultural and food chemistry, 60(25), 6399-6407 (2012-06-08)
Prostate cancer is one of the leading causes of cancer death in men in Western countries. Epidemiological studies have linked the consumption of fruits and vegetables to a reduced risk of prostate cancer, and small fruits are particularly rich sources
A novel combinatorial epigenetic therapy using resveratrol and pterostilbene for restoring estrogen receptor-alpha (ER alpha) expression in ER alpha-negative breast cancer cells
Kala R and Tollefsbol T O
PLoS ONE, 11(5), e0155057-e0155057 (2016)
Alle zugehörigen Dokumente anzeigen

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.