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15721

Sigma-Aldrich

Polydatin

≥95% (HPLC)

Synonym(e):

Piceid, Resveratrol 3-O-β-D-glucopyranosid, Resveratrol-3-β-mono-D-glucosid

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About This Item

Empirische Formel (Hill-System):
C20H22O8
CAS-Nummer:
65914-17-2
Molekulargewicht:
390.38
Beilstein:
54837
UNSPSC-Code:
12352201
PubChem Substanz-ID:
329750984
NACRES:
NA.25

Qualitätsniveau

100

Assay

≥95% (HPLC)

Form

powder

Optische Aktivität

[α]1/D -66.0±2.0° in ethanol

Zusammensetzung

carbon, 60.5-62.5%

Lagertemp.

2-8°C

SMILES String

OCC1O[C@@H](Oc2cc(O)cc(\C=C\c3ccc(O)cc3)c2)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C20H22O8/c21-10-16-17(24)18(25)19(26)20(28-16)27-15-8-12(7-14(23)9-15)2-1-11-3-5-13(22)6-4-11/h1-9,16-26H,10H2/b2-1+/t16?,17-,18+,19-,20-/m1/s1

InChIKey

HSTZMXCBWJGKHG-AEGFYQLOSA-N

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Anwendung

Polydatin, a type of polyphenolic phytoalexin, has many physiological and pharmacological effects including anti-inflammatory and anti-oxidative activities. Polydatin is an effective candidate drug for the protection of photo-inflammation. Polydatin exhibits therapeutic potential for vascular dementia, most likely due to its anti-oxidant activity and the direct protection of neurons.

Biochem./physiol. Wirkung

Stilbene found in medicinal herbs. Antioxidant, anti-inflammatory and neuroprotective.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Emodin-8-glucosid ≥95% (LC/MS-UV)

Sigma-Aldrich

SMB00546

Emodin-8-glucosid

Physcion ≥98.0% (TLC)

Sigma-Aldrich

17797

Physcion

4-Bromo-Resveratrol ≥98% (HPLC)

Sigma-Aldrich

SML1078

4-Bromo-Resveratrol

trans-Resveratrol United States Pharmacopeia (USP) Reference Standard

USP

1602105

trans-Resveratrol

ε-Viniferin phyproof® Reference Substance

PHL83550

ε-Viniferin

Isoliquiritin phyproof® Reference Substance

PHL80481

Isoliquiritin

Adstringin phyproof® Reference Substance

PHL80736

Adstringin

Hyunsu Park et al.
Journal of agricultural and food chemistry, 60(33), 8183-8189 (2012-07-25)
Piceid is widely used in food, cosmetics, and pharmaceuticals because of its therapeutic benefits. However, the use of piceid as a drug is limited because of its low solubility. To increase solubility, we synthesized piceid glucosides using maltosyltransferase from Caldicellulosiruptor
Jianxin Deng et al.
Journal of molecular and cellular cardiology, 53(5), 646-656 (2012-08-28)
Polydatin (PD), a resveratrol glucoside, has recently been suggested to have cardioprotective effects against heart diseases, including ischemia-reperfusion injury and pressure-overload induced ventricular remodeling. However, the mechanisms are poorly understood. This study aims to investigate the direct effects of PD
Jingming Zhang et al.
Molecular medicine reports, 6(4), 815-820 (2012-08-04)
The pathophysiology of non-alcoholic fatty liver disease remains incompletely elucidated, and available treatments are not entirely satisfactory. Polydatin, a stilbenoid compound derived from the rhizome of Polygonum cuspidatum, has been recognised to possess hepatoprotective and anti-inflammatory activities. The purpose of
Maria Rotches-Ribalta et al.
Pharmacological research, 66(5), 375-382 (2012-08-22)
A pharmacokinetic study of the metabolic profile of resveratrol has been performed in healthy men after moderate red wine (RW) consumption. The bioavailability of resveratrol is highly influenced by several factors such as the food matrix and, therefore, this study
Xingmin Wang et al.
Expert opinion on investigational drugs, 22(2), 169-179 (2012-12-18)
The aim of the study was find out whether neuronal mitochondrial injury does take place in severe shock and to explore effective therapy for severe shock. Rats were divided in the following group: sham, shock + normal saline (NS), shock
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