P0483

Anti-Potassium Channel SK2 antibody produced in rabbit

affinity isolated antibody, lyophilized powder

• Synonym(e): Apamin-Sensitive Conductance Ca2+-Dependent K+ Channel, KCa2, Kcnn2, SKCa2
• MDL-Nummer: MFCD02097223
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: lyophilized powder
• Speziesreaktivität: human, rat
• Methode(n): western blot (chemiluminescent): 1:200 using rat brain membranes
• UniProt-Hinterlegungsnummer: Q9H2S1
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: rat ... Kcnn2(54262)

Beschreibung

Allgemeine Beschreibung

Potassium calcium-activated channel subfamily N member 2 (KCNN2) or SK2 is expressed in rat Purkinje cells. The gene encoding this protein is localized on rat chromosome 18q11.

Immunogen

synthetic peptide corresponding to amino acids 542-559 of rat potassium channel SK2.

Anwendung

Anti-Potassium Channel SK2 (Apamin-Sensitive Conductance Ca²⁺-Dependent K⁺ Channel, KCa2, Kcnn2, SKCa2) antibody produced in rabbit has been used for immunohistochemistry and immunofluorescence.

Biochem./physiol. Wirkung

Potassium calcium-activated channel subfamily N member 2 (KCNN2) or SK2 has a role in the modulation of intrinsic excitability of neurons and Purkinje cells. It also has a role in synaptic transmission and plasticity. SK2 promotes hippocampus-dependent learning and memory in the mammalian brain.

Physikalische Form

Lyophilized at 0.3-1.4 mg/mL from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.025% - 0.050% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable