P0064

PalGly

≥98% (HPLC), solid

• Synonym(e): N-(1-Oxohexadecyl)-glycin, N-Hexadecanoylglycin
• Empirische Formel (Hill-System): C₁₈H₃₅NO₃
• CAS-Nummer: 2441-41-0
• Molekulargewicht: 313.48
• MDL-Nummer: MFCD00153471
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329820003
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: solid
• Farbe: white to off-white
• Löslichkeit: DMSO: >10 mg/mL
• Lagertemp.: 2-8°C
• SMILES String: O=C(CCCCCCCCCCCCCCC)NCC(O)=O
• InChI: 1S/C18H35NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17(20)19-16-18(21)22/h2-16H2,1H3,(H,19,20)(H,21,22)
• InChIKey: KVTFEOAKFFQCCX-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

PalGly is an endogenous signaling lipid that modulates calcium influx and nitric oxide production. PalGly inhibits heat-evoked firing of wide dynamic range (WDR) neurons, activates calcium influx in DRG cells and stimulates NO production. Preliminary studies suggest its signaling mechanism involves GPCR-mediated cation channel activation and a Gαi/o-coupled signaling pathway, which is being further investigated.

Leistungsmerkmale und Vorteile

This compound is featured on the Nitric Oxide Synthases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)