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O6004

Sigma-Aldrich

Octyl β-D-1-Thioglucopyranosid

≥98.0% (GC)

Synonym(e):

Octyl-thioglucosid

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About This Item

Empirische Formel (Hill-System):
C14H28O5S
CAS-Nummer:
85618-21-9
Molekulargewicht:
308.43
Beilstein:
4182783
MDL-Nummer:
MFCD00012189
UNSPSC-Code:
12352201
PubChem Substanz-ID:
24898030
NACRES:
NA.25

Biologische Quelle

synthetic

Qualitätsniveau

200

Beschreibung

non-ionic

Assay

≥98.0% (GC)

Form

crystalline

Optische Aktivität

[α]25/D -51 to -49 °, c = 1% (w/v) in ethanol

Mol-Gew.

308.43 g/mol

CMC

9 mM (20-25°C)

Lagertemp.

−20°C

SMILES String

CCCCCCCCS[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

InChI

1S/C14H28O5S/c1-2-3-4-5-6-7-8-20-14-13(18)12(17)11(16)10(9-15)19-14/h10-18H,2-9H2,1H3/t10-,11-,12+,13-,14+/m1/s1

InChIKey

CGVLVOOFCGWBCS-RGDJUOJXSA-N

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Anwendung

Octyl β-D-1-thioglucopyranoside can be used as a non-ionic detergent for solubilization and reconstitution of membrane proteins. It has been used in a study to assess the crystallization and preliminary x-ray analysis of human plasma apolipoprotein C-I. It has also been used in a study that investigated the identification of Chlamydia pneumoniae proteins.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

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K H Weisgraber et al.
Journal of molecular biology, 236(1), 382-384 (1994-02-11)
Human apolipoprotein C-I, the smallest of the plasma apolipoproteins, is a component of several classes of plasma lipoproteins. Two crystalline forms of this protein, both suitable for high resolution X-ray diffraction analysis, have been obtained from mixtures of 2-methyl-2,4-pentanediol, sodium
M Yoshida et al.
European journal of biochemistry, 222(3), 1055-1061 (1994-06-15)
Dystrophin is purified as a complex with several proteins from the digitonin-solubilized muscle cell membrane. Most of dystrophin-associated proteins (DAPs) are assumed to form a large oligomeric transmembranous glycoprotein complex on the sarcolemma and link dystrophin with a basement membrane
Sanghamitra Mukhopadhyay et al.
Molecular & cellular proteomics : MCP, 5(12), 2311-2318 (2006-08-22)
Chlamydia pneumoniae is an important human respiratory pathogen that is responsible for an estimated 10% of community-acquired pneumonia and 5% of bronchitis and sinusitis cases. We examined changes in global protein expression profiles associated with the redifferentiation of reticulate body
K Suzuki et al.
The Journal of pharmacology and experimental therapeutics, 288(1), 57-64 (1998-12-23)
A specific sugar-modified peptide has previously been shown to have renal targeting potential in vivo and to have a specific binding site which has been identified in the kidney membrane fraction. In this report, we studied the inhibitory effects of
Kraingkrai Ponhong et al.
Talanta, 87, 113-117 (2011-11-22)
A novel simultaneous injection effective mixing analysis system (SIEMA) for determination of direct bilirubin in urine sample was developed. Bilirubin reacts with diazotized sulfanilic acid in the presence of n-octyl-β-d-thioglucoside (OTG) as a solubilizing agent to form OTG-azobilirubin. The flow
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