M0567
Microsomes from Liver, Pooled
from human male
Synonym(e):
lab equipment accessory
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About This Item
UNSPSC-Code:
12352204
NACRES:
NA.54
Empfohlene Produkte
Biologische Quelle
human male
Qualitätsniveau
Form
liquid
Verpackung
vial of ~10 mg
Versandbedingung
dry ice
Lagertemp.
−70°C
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Anwendung
Microsomes from Liver, Pooled has been used:
- in the glucuronidation kinetics assay to test the effects of herbal extracts on glucuronidation process
- as a human liver microsomes (HLM) matrix for testing metabolic stability of talazoparib using liquid chromatography-tandem mass spectrometry (LC–MS/MS)
- to study the metabolization of enantiomeric peptide D3
Microsomes from liver have been used in a study to assess differences in enzymatic activities between normal rat livers and from liver after partial hepatectomy. They have also been used in a study to investigate the carbon monoxide-binding pigment in liver microsomes.
Biochem./physiol. Wirkung
Liver microsomes are subcellular particles derived from the endoplasmic reticulum of hepatic cells. These microsomes are a rich source of drug metabolizing enzymes, including cytochrome P-450. Microsome pools from various sources are useful in the study of xenobiotic metabolism and drug interactions.
N-glucuronidation of various 1-substituted imidazoles was found to occur in human liver microsomes.
Lagerklassenschlüssel
10 - Combustible liquids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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