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Merck

L9530

Sigma-Aldrich

Linoleic Acid-Albumin from bovine serum albumin

liquid, sterile-filtered, BioReagent, suitable for cell culture

Synonym(e):

Linoleic Acid-Albumin from BSA

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About This Item

UNSPSC-Code:
12352202
NACRES:
NA.75

Beschreibung

Contains 2 moles linoleic acid per mole BSA

Qualitätsniveau

Sterilität

sterile-filtered

Produktlinie

BioReagent

Form

liquid

Konzentration

100 mg/mL BSA in DPBS
90-120 mg/mL protein (biuret)

Methode(n)

cell culture | mammalian: suitable

Verunreinigungen

≤400 EU/mL endotoxin

Lagertemp.

2-8°C

Allgemeine Beschreibung

Fatty Acid-Albumin - complexes have been employed as alternative sources of lipids in the development of serum-free media. Fatty acids bind to serum proteins in high proportions. Such proteins may release beneficial fatty acids and bind those that are inhibitory. Linoleic acid, a precursor of prostaglandins bound to BSA is beneficial to the growth of a variety of cell types (e.g., BHK, hybridoma). It also improves its stability and solubility in culture media.

Anwendung

Linoleic Acid-Albumin from bovine serum albumin is used in the cell line culture and cell differentiation medium.
Linoleic Acid-Albumin from bovine serum albumin is used in the cell line culture and cell differentiation medium.

Sonstige Hinweise

Recommended usage: 1 ml/100 ml medium

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves


Analysenzertifikate (COA)

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Chiu-Fang Liang et al.
IUBMB life, 54(5), 275-279 (2003-02-18)
Epidermal growth factor (EGF) was reported to regulate triacyl glycerol synthesis in various cells. Linoleic acid and its metabolites were thought to modulate the signal transduction of growth factors. This study determined whether linoleic acid regulated the effect of EGF
Dong-Hwan Kim et al.
Lipids, 55(2), 163-171 (2020-02-15)
The regulation of adipocyte differentiation is an important factor for production efficiency and meat quality in the poultry industry. The purpose of this study was to develop a new in vitro model of adipogenic differentiation of chicken embryonic fibroblasts (CEF).
Doreen Reichert et al.
Cells, 10(4) (2021-05-01)
Chronic liver diseases are associated with excessive deposition of extracellular matrix proteins. This so-called fibrosis can progress to cirrhosis and impair vital functions of the liver. We examined whether the receptor tyrosine kinase (RTK) class III inhibitor Crenolanib affects the
Li-Ping Liu et al.
Cell reports, 27(2), 455-466 (2019-04-11)
Induced pluripotent stem cells (iPSCs) are a promising melanocyte source as they propagate indefinitely and can be established from patients. However, the in vivo functions of human iPSC-derived melanocytes (hiMels) remain unknown. Here, we generated hiMels from vitiligo patients using a three-dimensional
Cécile Coste et al.
PloS one, 12(7), e0177962-e0177962 (2017-07-07)
Adult neural crest stem-derived cells (NCSC) are of extraordinary high plasticity and promising candidates for use in regenerative medicine. Several locations such as skin, adipose tissue, dental pulp or bone marrow have been described in rodent, as sources of NCSC.

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