L6250

Lithocholsäure

≥95%

• Synonym(e): 3α-Hydroxy-5β-cholan-24-säure, 3α-Hydroxy-5β-cholansäure, 5β-Cholan-24-säure-3α-ol
• Empirische Formel (Hill-System): C₂₄H₄₀O₃
• CAS-Nummer: 434-13-9
• Molekulargewicht: 376.57
• Beilstein: 3217757
• EG-Nummer: 207-099-1
• MDL-Nummer: MFCD00003682
• UNSPSC-Code: 12352106
• PubChem Substanz-ID: 24896429
• NACRES: NA.25

Eigenschaften

• Biologische Quelle: bovine bile; synthetic
• Qualitätsniveau: 200
• Assay: ≥95%
• Mol-Gew.: 376.57 g/mol
• mp (Schmelzpunkt): 183-188 °C (lit.)
• Funktionelle Gruppe: carboxylic acid
• Versandbedingung: ambient
• Lagertemp.: room temp
• SMILES String: [H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC(O)=O)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
• InChI: 1S/C24H40O3/c1-15(4-9-22(26)27)19-7-8-20-18-6-5-16-14-17(25)10-12-23(16,2)21(18)11-13-24(19,20)3/h15-21,25H,4-14H2,1-3H3,(H,26,27)/t15-,16-,17-,18+,19-,20+,21+,23+,24-/m1/s1
• InChIKey: SMEROWZSTRWXGI-HVATVPOCSA-N
• Angaben zum Gen: human ... POLA1(5422) , TOP2A(7153) ; rat ... Polb(29240)

Beschreibung

Allgemeine Beschreibung

Lithocholic acid is an oligo(ethylene glycol) derivative of bile acid.

Anwendung

Lithocholic acid has been used in a study to assess cholestasis and its action on several organs and tissues in rats. It has also been used in a study to investigate the regulation of hepatic phospholipid and bile acid homeostasis through SMAD3 activation by TGFβ.

Biochem./physiol. Wirkung

Bile Acid

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)