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K3250

Sigma-Aldrich

Kynuramine dihydrobromide

monoamine oxidase substrate, fluorogenic, ≥97% (TLC), crystalline

Synonym(e):

3-(2-Aminophenyl)-3-oxopropanamine

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About This Item

Empirische Formel (Hill-System):
C9H12N2O · 2HBr
CAS-Nummer:
304-47-2
Molekulargewicht:
326.03
MDL-Nummer:
MFCD00050683
UNSPSC-Code:
12352204
PubChem Substanz-ID:
24896227
NACRES:
NA.32

product name

Kynuramine dihydrobromide, crystalline

Assay

≥97% (TLC)

Qualitätsniveau

100

Form

crystalline

Löslichkeit

water: 50 mg/mL, clear to slightly hazy

Lagertemp.

−20°C

SMILES String

Br.NCCC(=O)c1ccccc1N

InChI

1S/C9H12N2O.BrH/c10-6-5-9(12)7-3-1-2-4-8(7)11;/h1-4H,5-6,10-11H2;1H

InChIKey

YUPVVZSYBUIDQR-UHFFFAOYSA-N

Anwendung

Kynuramine dihydrobromide has been used as a substrate for monoamine oxidase.

Biochem./physiol. Wirkung

Kynuramine dihydrobromide is a substrate for the enzyme monoamine oxidase. The end product is the formation of fluorescence detectable 4-hydroxyquinoline (4-HOQ) measured in a fluorescence spectrophotometer at 380 nm.

Substrate

Substrate for monoamine oxidase

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

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Synergistic antidepressant-like effect of ferulic acid in combination with piperine: involvement of monoaminergic system
Li G, et al.
Metabolic Brain Disease, 30(6), 1505-1514 (2015)
Chronic dietary mercury exposure causes oxidative stress, brain lesions, and altered behaviour in Atlantic salmon (Salmo salar) parr
Berntssen MHG, et al.
Aquatic Toxicology (Amsterdam, Netherlands), 65(1), 55-72 (2003)
Magdalena S Nel et al.
Bioorganic chemistry, 69, 20-28 (2016-09-24)
In the present study a series of fifteen 2-heteroarylidene-1-indanone derivatives were synthesised and evaluated as inhibitors of recombinant human monoamine oxidase (MAO) A and B. These compounds are structurally related to series of heterocyclic chalcone derivatives which have previously been
Izaviany da Silva Schmitz et al.
Molecular biology reports, 46(2), 2285-2292 (2019-02-14)
Oxidative stress occurs due to an imbalance between antioxidant defenses and pro-oxidant agents in brain. This condition has been associated to the pathogenesis of several brain diseases; therefore, increasing the use of compounds that exert antioxidant activity. Thus, the objective
Paolo Guglielmi et al.
Molecules (Basel, Switzerland), 24(3) (2019-02-01)
New N-acetyl/N-thiocarbamoylpyrazoline derivatives were designed and synthesized in high yields to assess their inhibitory activity and selectivity against human monoamine oxidase A and B. The most important chiral compounds were separated into their single enantiomers and tested. The impact of
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