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I3275
Interferon-γ from rat
≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
Synonym(e):
IFN-γ
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About This Item
Empfohlene Produkte
Biologische Quelle
rat
Qualitätsniveau
Rekombinant
expressed in E. coli
Assay
≥97% (SDS-PAGE)
Form
lyophilized powder
Mol-Gew.
15.5 kDa
Verpackung
pkg of 0.1 mg
Methode(n)
cell culture | mammalian: suitable
Verunreinigungen
endotoxin, tested
Farbe
white
UniProt-Hinterlegungsnummer
Lagertemp.
−20°C
Angaben zum Gen
rat ... Ifng(25712)
Anwendung
Interferon-γ from rat has been used to study the effect of lipoxin A4 and 17(R)-resolvin D1 on lipopolysaccharide and interferon-γ-mediated tumor necrosis factor release in rat astrocyte culture. In rats, it has been used in the treatment of INS-1 cell culture to study the conversion factors which change the frequency of β-cell replication or apoptosis to rates of replication or apoptosis.
Biochem./physiol. Wirkung
Ifng (interferon-γ) plays an important role in innate and adaptive immune responses, and helps in defense against bacterial infections, dimorphic yeast and some viral infections. In rats, it is upregulated during ischemic injury in the embolic stroke. In cultured rat intestinal mucosa microvascular endothelial cells, ifng is responsible for inducing expression of interferon-α and interferon-β.
Leistungsmerkmale und Vorteile
The biological activity is measured in an anti-viral assay using L-929 cells infected with EMC virus.
Physikalische Form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 50 μg of bovine serum albumin per 1 μg of cytokine.
Ähnliches Produkt
Produkt-Nr.
Beschreibung
Preisangaben
Lagerklassenschlüssel
13 - Non Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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Meager, A. et al.
Lymphokines and Interferons, A Practical Approach, 129-129 (1987)
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PloS one, 8(9), e75543-e75543 (2013-10-03)
Lipoxins and resolvins have anti-inflammatory and pro-resolving actions and accumulating evidence indicates that these lipid mediators also attenuate pain-like behavior in a number of experimental models of inflammation and tissue injury-induced pain. The present study was undertaken to assess if
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iScience, 24(11), 103280-103280 (2021-11-13)
Nitric oxide (NO) is an important immune molecule that acts against extracellular and intracellular pathogens in most hosts. However, after the knockout of inducible nitric oxide synthase (iNOS -/-) in Sprague Dawley (SD) rats, these iNOS -/- rats were found
Hamid Reza Jafarinaveh et al.
Iranian journal of allergy, asthma, and immunology, 13(2), 125-130 (2013-12-18)
Increased levels of proinflammatory cytokines have been recorded after the onset of transient or permanent brain ischemia and are usually associated with exacerbation of ischemic injury. Embolic stroke model is more relevant to the pathophysiological situation in such patients, because
R Dijkema et al.
The EMBO journal, 4(3), 761-767 (1985-03-01)
The chromosomal immune interferon gene of the rat (IFN-gamma) was identified by screening a recombinant rat lambda phage library with a human IFN-gamma cDNA probe. In contrast to the genes of other rat IFNs, this rat IFN-gamma chromosomal gene contains
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