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Merck

I1536

Sigma-Aldrich

Isoorientin

≥98% (HPLC)

Synonym(e):

Homoorientin, Luteolin-6-C-β-D-glucosid, Luteolin-6-C-glucosid

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About This Item

Empirische Formel (Hill-System):
C21H20O11
CAS-Nummer:
Molekulargewicht:
448.38
MDL-Nummer:
UNSPSC-Code:
12352205
PubChem Substanz-ID:
NACRES:
NA.25

Biologische Quelle

leaves (Phyllostachya Nigra)

Qualitätsniveau

Assay

≥98% (HPLC)

Form

powder

Methode(n)

HPLC: suitable

Farbe

yellow

mp (Schmelzpunkt)

236 - 237  °C ( (457 - 459 °F))

Löslichkeit

methanol: 5 mg/mL, clear, colorless to yellow

Lagertemp.

2-8°C

SMILES String

OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc3OC(=CC(=O)c3c2O)c4ccc(O)c(O)c4

InChI

1S/C21H20O11/c22-6-14-17(27)19(29)20(30)21(32-14)16-11(26)5-13-15(18(16)28)10(25)4-12(31-13)7-1-2-8(23)9(24)3-7/h1-5,14,17,19-24,26-30H,6H2/t14-,17-,19+,20-,21+/m1/s1

InChIKey

ODBRNZZJSYPIDI-VJXVFPJBSA-N

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Anwendung


  • Exploring the therapeutic potential of isoorientin in the treatment of osteoporosis: a study using network pharmacology and experimental validation.: This research investigates isoorientin′s therapeutic potential in osteoporosis treatment, using network pharmacology and experimental methods to validate its efficacy (Zhang B et al., 2024).

Biochem./physiol. Wirkung

C-Glycosylflavon mit entzündungshemmenden, antimikrobiellen und antioxidativen Eigenschaften. Induziert antioxidative Reaktion durch PI3K-Signalisierung.

Sonstige Hinweise

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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Kunden haben sich ebenfalls angesehen

Slide 1 of 5

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Jinyong Peng et al.
Journal of chromatography. A, 1074(1-2), 111-115 (2005-06-09)
High-speed counter-current chromatography (HSCCC) with a solvent system composed of ethyl acetate-n-butanol-water (2:1:3, v/v/v) was used to isolate and separate two C-glycosylflavones from Patrinia villosa Juss, a traditional Chinese medicine. The separation produced 42.9 mg isovitexin and 20.1 mg isoorientin
Dong-Seon Kim et al.
Planta medica, 76(7), 678-682 (2009-12-05)
We aimed to find antiallergic agents from natural sources using mast cells activated during allergic reaction. We screened over 2000 plants for blockade of histamine release and identified two of them, S. baicalenesis and P. edulis. Bioassay-guided fractionation led to
Severina Pacifico et al.
Journal of natural products, 73(12), 1973-1978 (2010-11-18)
Eight flavonoid C-glycosides, including three new analogues, have been isolated from leaf and root methanolic extracts of Petrorhagia velutina, a Mediterranean herbaceous plant. The antiproliferative activity against human hepatoblastoma cancer cell line HepG2 has been analyzed by the MTT (3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium
Mala Ranghoo-Sanmukhiya et al.
Phytochemical analysis : PCA, 21(6), 566-574 (2010-09-08)
Aloe tormentorii, A. purpurea and A. macra are used as multipurpose folk medicines in Réunion and Mauritius Islands and are mistaken for the introduced Aloe vera. To compare the phytochemical, antimicrobial and DNA profiles of Aloe endemic to Mauritius and
Angel Josabad Alonso-Castro et al.
Endocrinology, 153(11), 5222-5230 (2012-09-06)
Isoorientin (ISO) is a plant C-glycosylflavonoid with purported antidiabetic effects but unexplored mechanisms of action. To gain insight into its antidiabetic mechanisms, we assayed nontoxic ISO concentrations on the 2-(N-(7-nitrobenz-2-oxa-1, 3-diazol-4-yl) amino)-2-deoxy-d-glucose (2-NBDG) uptake by murine 3T3-F442A and human sc

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