H2779
HistoChoice® Clearing Agent
alternative to toluene and xylene
Synonym(e):
dewaxing mixture for paraffin tissue sections
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Alle Fotos(1)
About This Item
UNSPSC-Code:
12171500
NACRES:
NA.47
Empfohlene Produkte
Qualitätsniveau
Form
liquid
Grünere Alternativprodukt-Eigenschaften
Designing Safer Chemicals
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
Farbe
colorless
Dichte
0.760-0.820 g/mL
Anwendung(en)
hematology
histology
Grünere Alternativprodukt-Kategorie
, Aligned
Lagertemp.
room temp
Allgemeine Beschreibung
HistoChoice® is a patented, complex mixture of agents that allow tissues to retain their structure, antigenic sites, and nucleic acid sites. It is a non-toxic, non-cross-linking fixative formulated to replace formaldehyde-based fixation. This formulation in non-citrus, contains no mercury, formaldehyde, or glutaraldehyde.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has Inherently Safer Chemistry, compared to the standard use of formalin for tissue processing.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has Inherently Safer Chemistry, compared to the standard use of formalin for tissue processing.
Anwendung
HistoChoice® Clearing Agent has the following applications:
- It is suitable as an alternative to toluene and xylene for dewaxing paraffin tissue sections. Prepared slides are suitable for antibody probing applications and in situ hybridizations.
- It has been employed in a study to explain the recalcitrance of lignocellulosic plant cell walls to enzymatic degradation.
- It has been used to develop a novel method to improve sensitivity for the localization of miRNA and their target transcripts in plants.
- It has been used to study the correlation of cytoplasmic ADP-ribosylation levels with markers of patient outcome in human cancers.
Biochem./physiol. Wirkung
Fixation with HistoChoice® works well in immunohistology applications where its non-cross-linking traits are conducive to epitope retrieval and identification by primary antibodies to extracellular matrix components.
Leistungsmerkmale und Vorteile
- Non-toxic, non-carcinogenic, and odorless.
- Non-flammable.
- Preserves native antigenic and nucleic acid sites.
- Compatible with many organic mounting media.
- Dissolves wax faster and evaporates slower than xylene.
- Can be used in automated processors.
- Tissues retain their original structure.
Rechtliche Hinweise
HistoChoice is a registered trademark of Amresco, Inc.
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Zielorgane
Respiratory system
Lagerklassenschlüssel
10 - Combustible liquids
WGK
WGK 3
Flammpunkt (°F)
142.0 °F
Flammpunkt (°C)
61.1 °C
Persönliche Schutzausrüstung
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
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Anita S Patel et al.
The Journal of investigative dermatology, 128(12), 2888-2893 (2008-06-13)
An increasing number of studies report that genus beta human papillomaviruses (HPVs) are associated with skin cancer, with suggestions of specificity for squamous cell carcinoma (SCC) of the skin. We have conducted a systematic examination of HPV DNA in tumors
Marie-Françoise Devaux et al.
Frontiers in plant science, 9, 200-200 (2018-03-09)
Tracking enzyme localization and following the local biochemical modification of the substrate should help explain the recalcitrance of lignocellulosic plant cell walls to enzymatic degradation. Time-lapse studies using conventional imaging require enzyme labeling and following the biochemical modifications of biopolymers
Synchrotron Time-Lapse Imaging of Lignocellulosic Biomass Hydrolysis: Tracking Enzyme Localization by Protein Autofluorescence and Biochemical Modification of Cell Walls by Microfluidic Infrared Microspectroscopy
Devaux, et al.
Frontiers in Plant Science (2018)
Sathyanesan Samuel Newton et al.
Brain research. Brain research protocols, 9(3), 214-219 (2002-07-13)
A method is described to perform combined immunohistochemistry and in situ hybridization in mouse brain sections. The protocol is specific to sections mounted on glass slides. In contrast to earlier methods that require either paraffin embedding or perfusion of the
Cytoplasmic ADP-ribosylation levels correlate with markers of patient outcome in distinct human cancers
Aimi, et al.
Modern Pathology (2021)
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