G5146

D-(+)-Glukose

Hybri-Max^™, powder, BioReagent, suitable for hybridoma

• Synonym(e): Dextrose
• Empirische Formel (Hill-System): C₆H₁₂O₆
• CAS-Nummer: 50-99-7
• Molekulargewicht: 180.16
• Beilstein: 1724615
• EG-Nummer: 200-075-1
• MDL-Nummer: MFCD00063774
• UNSPSC-Code: 12352201
• PubChem Substanz-ID: 24895199
• NACRES: NA.75

Eigenschaften

• Biologische Quelle: maize
• Qualitätsniveau: 200
• Qualität: Hybri-Max^™
• Produktlinie: BioReagent
• Assay: ≥99.5%
• Form: powder
• Methode(n): cell culture | hybridoma: suitable
• Verunreinigungen: endotoxin, tested
• mp (Schmelzpunkt): 150-152 °C (lit.)
• Löslichkeit: H₂O: 2g + 15 mL (Tested)
• SMILES String: OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
• InChI: 1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
• InChIKey: WQZGKKKJIJFFOK-DVKNGEFBSA-N
• Angaben zum Gen: human ... PYGM(5837)

Beschreibung

Allgemeine Beschreibung

Glycogen phosphorylase (PYG) exists as brain and muscle isoform. It is expressed in astrocytes and neurons respectively. The PYGM gene is mapped to human chromosome 11q13.1.

Anwendung

D-(+)-Glucose has been used in cell engineering. It has also been used to perform oral glucose tolerance test.

Biochem./physiol. Wirkung

Glycogen phosphorylase, muscle associated (PYGM), is an important contributor to glycogenolysis. Down regulation of PYGM gene is observed in schizophrenia. Mutation in PYGM leads to McArdle disease, a glycogen storage disorder. The PYGM gene is significantly associated with energy production.

Angaben zur Herstellung

The material may produce a yellowish solution if prepared at a higher concentration than 2g + 15ml.

Rechtliche Hinweise

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)