F6889

Famotidin

• Synonym(e): N′-(Aminosulfonyl)-3-{[2-(diaminomethylenamino)-4-thiazolyl]-methylthio}-propanamidin
• Empirische Formel (Hill-System): C₈H₁₅N₇O₂S₃
• CAS-Nummer: 76824-35-6
• Molekulargewicht: 337.45
• MDL-Nummer: MFCD00079297
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24278442
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Ersteller: Johnson & Johnson
• SMILES String: N\C(N)=N\c1nc(CSCCC(=N)NS(N)(=O)=O)cs1
• InChI: 1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)
• InChIKey: XUFQPHANEAPEMJ-UHFFFAOYSA-N
• Angaben zum Gen: human ... HRH2(3274)

Beschreibung

Anwendung

Famotidine has been used to test its effect on the human ether-a-go-go-related gene (hERG) binding transfected in HEK293 membrane. It has also been used in polycaprolactone based drug delivery studies.

Biochem./physiol. Wirkung

Famotidine is not effective on muscarinic and nicotinic receptors. It competitively inhibits the secretion of gastric acid and elicits mucosal injury protection.

H₂ Histamin-Rezeptorantagonist; Antiulcusmittel

Leistungsmerkmale und Vorteile

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)