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Merck

F5897

Sigma-Aldrich

Anti-Mouse IgG (Fc specific)–FITC antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(e):

Goat Anti-Mouse IgG (Fc specific)–Fluorescein isothiocyanate

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About This Item

MDL-Nummer:
UNSPSC-Code:
12352203
NACRES:
NA.46

Biologische Quelle

goat

Qualitätsniveau

Konjugat

FITC conjugate

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

secondary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Lagerbedingungen

protect from light

Methode(n)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200
indirect immunofluorescence: 1:64

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

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Allgemeine Beschreibung

IgG subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids.

Spezifität

Anti-Mouse IgG (Fc specific)-FITC antibody is specific for Fc fragment of all mouse IgG subclasses. It shows no reactivity with mouse IgG Fab fragment, rat IgG or human IgG. Goat anti-Mouse IgG is conjugated to FITC and then purified by gel filtration to remove free FITC.

Immunogen

Purified mouse IgG

Anwendung

Anti-Mouse IgG (Fc specific)−FITC antibody produced in goat has been used in:
  • immunohistochemistry
  • immunofluorescence
  • anti-nuclear antibody assay

Biochem./physiol. Wirkung

IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections.

Sonstige Hinweise

Antibody adsorbed with human IgG and rat serum proteins.

Physikalische Form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Angaben zur Herstellung

Adsorbed to reduce background staining with human or rat samples.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

IgG subclasses and allotypes: from structure to effector functions
Vidarsson G, et al.
Frontiers in Immunology, 5 (2014)
JmjC domain-containing protein 6 (Jmjd6) derepresses the transcriptional repressor transcription factor 7-like 1 (Tcf7l1) and is required for body axis patterning during xenopus embryogenesis
Zhang X, et al.
The Journal of Biological Chemistry, 290(33), 20273-20283 (2015)
Two NOD Idd-associated intervals contribute synergistically to the development of autoimmune exocrinopathy (Sjogren's syndrome) on a healthy murine background
Cha S, et al.
Arthritis and Rheumatism, 46(5), 1390-1398 (2002)
Reelin signaling is necessary for a specific step in the migration of hindbrain efferent neurons
Rossel M, et al.
Development, 132(6), 1175-1185 (2005)
B cells, antibodies, and more
Hoffman W, et al.
Clinical journal of the American Society of Nephrology : CJASN, 11(1), 137-154 (2016)

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