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Merck

D6375

Sigma-Aldrich

2′-Desoxyadenosin 5′-Monophosphat

Sigma Grade, 98-100%

Synonym(e):

2′-Deoxy-AMP, 2′-Deoxyadenylic acid, dAMP

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About This Item

Empirische Formel (Hill-System):
C10H14N5O6P
CAS-Nummer:
Molekulargewicht:
331.22
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41106305
eCl@ss:
32160414
PubChem Substanz-ID:
NACRES:
NA.51

Biologische Quelle

synthetic (organic)

Qualitätsniveau

Qualität

Sigma Grade

Assay

98-100%

Form

powder

Löslichkeit

1 N NH4OH: 50 mg/mL, clear, colorless

Lagertemp.

−20°C

SMILES String

Nc1ncnc2n(cnc12)[C@H]3C[C@H](O)[C@@H](COP(O)(O)=O)O3

InChI

1S/C10H14N5O6P/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(21-7)2-20-22(17,18)19/h3-7,16H,1-2H2,(H2,11,12,13)(H2,17,18,19)/t5-,6+,7+/m0/s1

InChIKey

KHWCHTKSEGGWEX-RRKCRQDMSA-N

Allgemeine Beschreibung

N2′-Deoxyadenosine 5′-monophosphate is a nucleotide that serves as a building block for DNA synthesis.

Anwendung

2’-deoxyadenosine-5’-monophosphatehas been used to study proteins via UV resonance Raman spectroscopy.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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UV-A radiation (320-400 nm) induces damages to the DNA molecule and its components through photosensitized reactions. Pterins, heterocyclic compounds widespread in biological systems, participate in relevant biological processes and are able to act as photosensitizers. We have investigated the photosensitization
Joe A B McCann et al.
Journal of the American Chemical Society, 129(22), 7055-7064 (2007-05-15)
Multiple kinetic isotope effects (KIEs) on deoxyadenosine monophosphate (dAMP) hydrolysis in 0.1 M HCl were used to determine the transition state (TS) structure and probe its intrinsic reactivity. The experimental KIEs revealed a stepwise (SN1) mechanism, with a discrete oxacarbenium
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