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Merck

C4032

Sigma-Aldrich

Casein, Dephosphorylated from bovine milk

lyophilized powder

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About This Item

CAS-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352202
NACRES:
NA.61

Biologische Quelle

bovine milk

Qualitätsniveau

Assay

≥85% (biuret)

Form

lyophilized powder

UniProt-Hinterlegungsnummer

Lagertemp.

2-8°C

InChI

1S/C81H125N22O39P/c1-36(2)31-50(76(132)94-43(15-24-57(87)108)71(127)101-52(34-64(120)121)78(134)98-49(81(137)138)11-7-8-30-82)99-72(128)47(19-28-61(114)115)95-77(133)51(33-63(118)119)100-73(129)48(20-29-62(116)117)97-80(136)65(37(3)104)103-75(131)44(16-25-58(88)109)92-68(124)42(14-23-56(86)107)90-67(123)41(13-22-55(85)106)91-69(125)45(17-26-59(110)111)93-70(126)46(18-27-60(112)113)96-79(135)53(35-142-143(139,140)141)102-74(130)40(12-21-54(84)105)89-66(122)39(83)32-38-9-5-4-6-10-38/h4-6,9-10,36-37,39-53,65,104H,7-8,11-35,82-83H2,1-3H3,(H2,84,105)(H2,85,106)(H2,86,107)(H2,87,108)(H2,88,109)(H,89,122)(H,90,123)(H,91,125)(H,92,124)(H,93,126)(H,94,132)(H,95,133)(H,96,135)(H,97,136)(H,98,134)(H,99,128)(H,100,129)(H,101,127)(H,102,130)(H,103,131)(H,110,111)(H,112,113)(H,114,115)(H,116,117)(H,118,119)(H,120,121)(H,137,138)(H2,139,140,141)

InChIKey

BECPQYXYKAMYBN-UHFFFAOYSA-N

Angaben zum Gen

Allgemeine Beschreibung

Dephosphorylated casein is prepared by the action of potato acid phosphatase. It displays improved solubility and less foaming.

Anwendung

Casein, Dephosphorylated from bovine milk has been used as a substrate in in vitro kinase assays of Arabidopsis thaliana GSK3/Shaggy like kinase, casein kinase II and NIMA (never in mitosis A)-related kinase 2 (Nek2).

Biochem./physiol. Wirkung

Clusters of phosphoserine in casein chelate iron and reduce its bioavailability. Partial enzymatic digestion of casein unmasks phosphorylated residues to alkaline phosphatase, permitting dephosphorylation and increasing the bioavailability of iron.
Dephosphorylated casein lacks a net negative charge and is less sensitive to calcium. It is useful in food industry.

Qualität

At least 70% dephosphorylated.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

The Arabidopsis thaliana GSK3/Shaggy like kinase AtSK3-2 modulates floral cell expansion
Claisse G, et al.
Plant Molecular Biology, 64(1-2) (2007)
Marie Lawson et al.
European journal of medicinal chemistry, 123, 105-114 (2016-07-31)
We report here the synthesis, the biological evaluation and the molecular modeling studies of new imidazo[1,2-a]pyridines derivatives designed as potent kinase inhibitors. This collection was obtained from 2-aminopyridines and 2-bromoacetophenone which afforded final compound in only one step. The bioactivity
Functional Properties of Dephosphorylated Bovine Whole Casein1
Van Hekken DL and Strange, ED
Journal of Dairy Science, 76(11) (1993)
Casein, Dephosphorylated, has been used in studies of modulators of circadian clocks. It has been shown that several molecules can inhibit casein kinase which results in the lenghthening of these clocks.
Chen, Z., et al.
Proceedings of the National Academy of Sciences of the USA (2011)
v-Src-dependent down-regulation of the Ste20-like kinase SLK by casein kinase II
Chaar Z, et al.
Test, 281(38) (2006)

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