B9636

S-Benzoylthiamine O-monophosphate

• Synonym(e): Benfotiamine
• Empirische Formel (Hill-System): C₁₉H₂₃N₄O₆PS
• CAS-Nummer: 22457-89-2
• Molekulargewicht: 466.45
• EG-Nummer: 245-013-4
• MDL-Nummer: MFCD00057343
• UNSPSC-Code: 12352116
• PubChem Substanz-ID: 24892147
• NACRES: NA.79

Eigenschaften

• Assay: ≥98% (TLC)
• Qualitätsniveau: 200
• Form: powder or crystals
• Farbe: white to off-white
• Lagertemp.: 2-8°C
• SMILES String: Cc1ncc(CN(C=O)\C(C)=C(/CCOP(O)(O)=O)SC(=O)c2ccccc2)c(N)n1
• InChI: 1S/C19H23N4O6PS/c1-13(23(12-24)11-16-10-21-14(2)22-18(16)20)17(8-9-29-30(26,27)28)31-19(25)15-6-4-3-5-7-15/h3-7,10,12H,8-9,11H2,1-2H3,(H2,20,21,22)(H2,26,27,28)/b17-13+
• InChIKey: BTNNPSLJPBRMLZ-GHRIWEEISA-N

Beschreibung

Allgemeine Beschreibung

S-Benzoylthiamine O-monophosphate (Benfotiamine) is an amphiphilic S-acyl thiamine derivative. It is a lipid-soluble vitamin. Benfotiamine contains a thiazole ring. Benfotiamine has a greater bioavailability than thiamine.

Anwendung

S-Benzoylthiamine O-monophosphate has been used to determine its effect on ischemia and reperfusion in skeletal muscles of rat.

Biochem./physiol. Wirkung

S-Benzoylthiamine O-monophosphate (Benfotiamine) is a therapeutic agent. It helps in the prevention of diabetic complications such as, retinopathy, neuropathy and nephropathy. Benfotiamine inhibits the synthesis of glycation end products (AGEs) in diabetes. Benfotiamine is considered as a nutraceutical product for the prevention of diabetic neuropathy.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)