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B7688

Sigma-Aldrich

PiB

≥98% (HPLC)

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About This Item

Empirische Formel (Hill-System):
C22H18N2O8
CAS-Nummer:
64005-90-9
Molekulargewicht:
438.39
MDL-Nummer:
MFCD00333607
UNSPSC-Code:
12352200
PubChem Substanz-ID:
329773301
NACRES:
NA.77

Qualitätsniveau

100

Assay

≥98% (HPLC)

Form

powder

Farbe

white to light brown

Löslichkeit

DMSO: 1-2 mg/mL (warmed)

Lagertemp.

2-8°C

SMILES String

O=C(C1=C2C(C3=CC=C24)=C(C(N(CC(OCC)=O)C3=O)=O)C=C1)N(CC(OCC)=O)C4=O

InChI

1S/C22H18N2O8/c1-3-31-15(25)9-23-19(27)11-5-7-13-18-14(8-6-12(17(11)18)20(23)28)22(30)24(21(13)29)10-16(26)32-4-2/h5-8H,3-4,9-10H2,1-2H3

InChIKey

WNKQGFNIIHNGQM-UHFFFAOYSA-N

Biochem./physiol. Wirkung

PiB is a Pin-1 inhibitor.
PiB is an inhibitor of the peptidylprolyl isomerase Pin-1. Inhibition of Pin-1 leads to destabilization of the transcription factor Nanog, which is required for maintenance of embryonic stem cell cultures.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Analysenzertifikate (COA)

Lot/Batch Number
123M4603V
120M4621V

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