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Merck

B7639

Sigma-Aldrich

(+)-Biotinhydrazid

≥97% (TLC), powder

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About This Item

Empirische Formel (Hill-System):
C10H18N4O2S
CAS-Nummer:
Molekulargewicht:
258.34
Beilstein:
28347
MDL-Nummer:
UNSPSC-Code:
12352203
PubChem Substanz-ID:
NACRES:
NA.46

Qualitätsniveau

Assay

≥97% (TLC)

Form

powder

Löslichkeit

DMSO: ≤20 mg/mL

Lagertemp.

2-8°C

SMILES String

[H][C@]12CS[C@@H](CCCCC(=O)NN)[C@@]1([H])NC(=O)N2

InChI

1S/C10H18N4O2S/c11-14-8(15)4-2-1-3-7-9-6(5-17-7)12-10(16)13-9/h6-7,9H,1-5,11H2,(H,14,15)(H2,12,13,16)/t6-,7-,9-/m0/s1

InChIKey

KOZWHQPRAOJMBN-ZKWXMUAHSA-N

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Allgemeine Beschreibung

Biotin hydrazide is a biotinylation reagent used to biotinylate glycoproteins with their sugar moieties. Biotin hydrazide can be used to prepare biotin-conjugated alginate. It can also be used for covalent attachment to PAAc via carbodi-imide cross linking.

Anwendung

(+)-Biotin hydrazide has been used:
  • the modification of alginate
  • for the labelling of mitochondrial proteins from non-muscle tissues
  • as a component of glycoprotein staining solution
  • in periodic acid-biotin-hydrazide (PABH) assay for mucins
  • for labeling surface functional groups, biologically active molecules such as antibodies, lectins, sugars, nucleic acids or molecules with free carboxylic or keto groups.
  • for coupling to glycoproteins through the carbohydrate by hydrazone formation

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Produkt-Nr.
Beschreibung
Preisangaben

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Die Dokumentenbibliothek aufrufen

Studying mucin secretion from human bronchial epithelial cell primary cultures
Mucins, 259-277 (2012)
Boris Polyak et al.
Biomacromolecules, 5(2), 389-396 (2004-03-09)
Biotin was covalently coupled with alginate in an aqueous-phase reaction by means of carbodiimide-mediated activation chemistry to provide a biotin-alginate conjugate for subsequent use in biosensor applications. The synthetic procedure was optimized with respect to pH of the reaction medium
Kazumi Ninomiya et al.
Nutrients, 10(10) (2018-10-18)
Inhibiting starch hydrolysis into sugar could reduce postprandial blood glucose elevation and contribute to diabetes prevention. Here, both buckwheat and wheat albumin that inhibited mammalian α-amylase in vitro suppressed blood glucose level elevation after starch loading in vivo, but it
Enhanced capture and release of circulating tumor cells using hollow glass microspheres with a nanostructured surface
Dong Z, et al.
Nanoscale, 10(35), 16795-16804 (2018)
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Analytical chemistry, 84(8), 3682-3688 (2012-03-15)
Microfluidic systems for affinity-based cell isolation have emerged as a promising approach for the isolation of specific cells from complex matrices (i.e., circulating tumor cells in whole blood). However, these technologies remain limited by the lack of reliable methods for

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