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Merck

A9555

Sigma-Aldrich

Monoclonal Anti-Aflatoxin B1 (G1, Q1, B2, G2) antibody produced in mouse

clone AT-B1, ascites fluid

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About This Item

MDL-Nummer:
UNSPSC-Code:
12352203
NACRES:
NA.46

Biologische Quelle

mouse

Qualitätsniveau

Konjugat

unconjugated

Antikörperform

ascites fluid

Antikörper-Produkttyp

primary antibodies

Klon

AT-B1, monoclonal

Enthält

15 mM sodium azide

Methode(n)

ELISA: 1:20,000 using aflatoxin B1-BSA

Isotyp

IgG1

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Allgemeine Beschreibung

Monoclonal anti-Aflatoxin B (mouse IgG1 isotype) is 1 derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.Aflatoxins are a group of naturally occurring fungal toxins (mycotoxins) synthesized by Aspergillus flavus and Aspergillus parasiticus. It is found as contaminants in human and animal food such as corn, peanuts, tree nuts, cottonseed, cereal crops, beans, casssava, milo, sorghum, copra, rice, dried fish and beer.

Immunogen

aflatoxin B -KLH conjugate

Anwendung

Monoclonal Anti-Aflatoxin B1 (G1, Q1, B2, G2) antibody produced in mouse has been used in indirect enzyme linked immunosorbent assay (ELISA) and fluorescence polarization assay.

Biochem./physiol. Wirkung

Aflatoxin B (AFB) and its metabolites is known to act as potent carcinogens, mutagens and teratogens, in addition to its toxicity. Aflatoxins have been implicated in human hepatocellular carcinoma, outbreaks of aflatoxicosis, Rey′s syndrome, chronic hepatitis and increased mortality from infection in animal husbandry.

Zielbeschreibung

Mycotoxins, a group of chemically diverse secondary fungal metabolites, induce a variety of toxic responses in humans and animals when food and feed containing these compounds are ingested. Rapidly quantitating levels of mycotoxin contamination can help reduce exposure to these toxins.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Screening of Lactobacillus casei strains for their ability to bind aflatoxin B1
Hernandez MA, et al.
Food And Chemical Toxicology, 47(6), 1064-1068 (2009)
Robert J Lee et al.
Scientific reports, 6, 33221-33221 (2016-09-15)
Aflatoxins are mycotoxins secreted by Aspergillus flavus, which can colonize the respiratory tract and cause fungal rhinosinusitis or bronchopulmonary aspergillosis. A. flavus is the second leading cause of invasive aspergillosis worldwide. Because many respiratory pathogens secrete toxins to impair mucociliary
Physicochemical and immunological characterization of chitosan-coated bacteriophage nanoparticles for in vivo mycotoxin modeling
de Andrade CYT, et al.
Carbohydrate Polymers, 185, 63-72 (2018)
Development of a fluorescence polarization assay for the determination of aflatoxins in grains
Nasir MS and Jolley ME
Journal of Agricultural and Food Chemistry, 50(11), 3116-3121 (2002)
Frances A Draughon et al.
Journal of food protection, 45(8), 703-706 (1982-06-01)
Aflatoxin B1 was mixed with eleven concentrations of sodium hydroxide, sodium hypochlorite and ammonium hydroxide. Aflatoxin was quantitated by fluorometric determination and toxicity of aflatoxin treated with NaOH and NH4OH was evaluated by the brine shrimp assay. Detoxified aflatoxin B1

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