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Merck

53163

Sigma-Aldrich

Hyaluronsäure Natriumsalz aus Streptococcus equi sp.

mol wt 750,000-1,000,000

Synonym(e):

Natrium-hyaluronat

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About This Item

CAS-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352201
NACRES:
NA.25

Biologische Quelle

(Streptococcus equi)

Qualitätsniveau

Form

powder

Mol-Gew.

750,000-1,000,000

Farbe

white

Löslichkeit

water: ~5 g/L

Eignung

conforms to structure for Infrared spectrum

Versandbedingung

wet ice

Lagertemp.

−20°C

InChI

1S/C28H44N2O23.Na/c1-5(33)29-9-18(11(35)7(3-31)47-25(9)46)49-28-17(41)15(39)20(22(53-28)24(44)45)51-26-10(30-6(2)34)19(12(36)8(4-32)48-26)50-27-16(40)13(37)14(38)21(52-27)23(42)43;/h7-22,25-28,31-32,35-41,46H,3-4H2,1-2H3,(H,29,33)(H,30,34)(H,42,43)(H,44,45);/q;+1/t7-,8-,9-,10-,11-,12-,13+,14+,15-,16-,17-,18-,19-,20+,21+,22+,25-,26+,27-,28-;/m1./s1

InChIKey

YWIVKILSMZOHHF-QJZPQSOGSA-N

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Anwendung

suitable as substrate for hyaluronidase

Sonstige Hinweise

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Dianhua Jiang et al.
Physiological reviews, 91(1), 221-264 (2011-01-21)
Accumulation and turnover of extracellular matrix components are the hallmarks of tissue injury. Fragmented hyaluronan stimulates the expression of inflammatory genes by a variety of immune cells at the injury site. Hyaluronan binds to a number of cell surface proteins
H Porsch et al.
Oncogene, 32(37), 4355-4365 (2012-10-31)
Epithelial-mesenchymal transition (EMT) is a developmental program, which can be adopted by cancer cells to increase their migration and ability to form metastases. Transforming growth factor β (TGFβ) is a well-studied inducer of EMT. We demonstrate that TGFβ potently stimulates
J Ye et al.
Eye (London, England), 26(7), 1012-1020 (2012-05-19)
To investigate the toxic effects of ethylenediaminetetraacetic acid disodium salt (EDTA), a corneal penetration enhancer in topical ophthalmic formulations, on DNA in human corneal epithelial cells (HCEs), and to investigate whether the effect induced by EDTA can be inhibited by
Melissa R Junttila et al.
Nature, 501(7467), 346-354 (2013-09-21)
Tumour formation involves the co-evolution of neoplastic cells together with extracellular matrix, tumour vasculature and immune cells. Successful outgrowth of tumours and eventual metastasis is not determined solely by genetic alterations in tumour cells, but also by the fitness advantage
Aimin Wang et al.
The Journal of biological chemistry, 289(16), 11410-11420 (2014-02-27)
Isolated rat bone marrow stromal cells cultured in osteogenic medium in which the normal 5.6 mm glucose is changed to hyperglycemic 25.6 mm glucose greatly increase lipid formation between 21-31 days of culture that is associated with decreased biomineralization, up-regulate

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