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50839

Sigma-Aldrich

Catalpol

≥96% (HPLC)

Synonym(e):

(1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)-oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-β-D-glucopyranosid, Catalpinosid, De(p-hydroxybenzoyl)-catalposid

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About This Item

Empirische Formel (Hill-System):
C15H22O10
CAS-Nummer:
2415-24-9
Molekulargewicht:
362.33
EG-Nummer:
219-324-0
MDL-Nummer:
MFCD11111524
UNSPSC-Code:
12352211
PubChem Substanz-ID:
329757639
NACRES:
NA.25

Qualitätsniveau

100

Assay

≥96% (HPLC)

Lagertemp.

−20°C

SMILES String

OC[C@H]1O[C@@H](O[C@@H]2OC=C[C@H]3[C@H](O)[C@@H]4O[C@]4(CO)[C@@H]23)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C15H22O10/c16-3-6-9(19)10(20)11(21)14(23-6)24-13-7-5(1-2-22-13)8(18)12-15(7,4-17)25-12/h1-2,5-14,16-21H,3-4H2/t5-,6-,7-,8+,9-,10+,11-,12+,13+,14+,15-/m1/s1

InChIKey

LHDWRKICQLTVDL-PZYDOOQISA-N

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Biochem./physiol. Wirkung

The primary function is to stimulate the production of adrenal cortical hormones, which increases the production of sex hormones. Catalpol also exhibits anti-inflammatory activity and has shown to increase the production of androgens yielded by the adrenal gland, which can lead to increases in muscle mass.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Sigma-Aldrich

L4391

Lipopolysaccharide aus Escherichia coli O111:B4

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A large body of evidence suggests that the inflammatory reaction plays an important role in the pathogenesis of neurodegenerative diseases. Our previous studies described the neuroprotective effects of catalpol in lipopolysaccharide (LPS)-induced inflammatory models, in which catalpol was shown to
Analysis of catalpol derivatives by characteristic neutral losses using liquid chromatography combined with electrospray ionization multistage and time-of-flight mass spectrometry.
Jun-Li Hong et al.
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Hui-Feng Zhu et al.
International journal of biological sciences, 6(5), 443-453 (2010-09-10)
To investigate the role and mechanism of catalpol in brain angiogenesis in a rat model of stroke, the effect of catalpol (5 mg/kg; i.p) or vehicle administered 24 hours after permanent middle cerebral artery occlusion (pMCAO) on behavior, angiogenesis, ultra-structural
Zhiming Xia et al.
Brain research, 1441, 27-37 (2012-02-07)
Our previous studies demonstrate that a non-cholinesterase inhibitor (AChEI) compound catalpol, purified from a traditional Chinese medicinal herb Rehmannia glutinosa, could improve the symptoms and pathological changes in animal and cellular models of memory related neurodegenerative diseases. In this study
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