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Merck

44977

Sigma-Aldrich

DISBAC2(3), spannungssensitive Sonde

≥98% (HPLC)

Synonym(e):

5-[3-(1,3-Diethylhexahydro-4,6-dioxo-2-thioxo-5-pyrimidinyl)-2-propen-1-yliden]-1,3-diethyldihydro-2-thioxo-4,6(1H,5H)-pyrimidindion, Bis-(1,3-diethylthiobarbitursäure)-trimethinoxonol

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About This Item

Empirische Formel (Hill-System):
C19H24N4O4S2
CAS-Nummer:
Molekulargewicht:
436.55
Beilstein:
1232950
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352108
PubChem Substanz-ID:
NACRES:
NA.32

Qualitätsniveau

Assay

≥98% (HPLC)

Fluoreszenz

λex 535 nm; λem 560 nm in DMSO

Eignung

complies for Infrared spectrum

Lagertemp.

−20°C

SMILES String

CCN1C(=O)C(\C=C\C=C2\C(=O)N(CC)C(=S)N(CC)C2=O)C(=O)N(CC)C1=S

InChI

1S/C19H24N4O4S2/c1-5-20-14(24)12(15(25)21(6-2)18(20)28)10-9-11-13-16(26)22(7-3)19(29)23(8-4)17(13)27/h9-12H,5-8H2,1-4H3/b10-9+

InChIKey

VJYNRXFXHKIGLT-MDZDMXLPSA-N

Anwendung

DISBAC2(3), Voltage Sensitive Probe is used for single-cell fluorescence imaging of transmembrane conductance and potential change.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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P He et al.
Microvascular research, 50(2), 183-198 (1995-09-01)
The membrane potential is an important modulator of calcium ion flux into endothelial cells of venular microvessels. We developed a method to measure the membrane potential of endothelial cells forming the walls of individually perfused microvessels under the same experimental
A B Al-Mehdi et al.
American journal of respiratory cell and molecular biology, 18(5), 653-661 (1998-06-06)
We hypothesize that lung ischemic injury is related to cessation of flow leading to endothelial cell membrane depolarization and activation of oxidant-generating systems. Cell membrane potential was assessed in isolated, oxygen ventilated, Krebs-Ringer bicarbonate buffer-dextran-perfused rat lungs by lung surface
Konstantinos Papadimitriou et al.
International journal of food microbiology, 111(3), 197-205 (2006-08-29)
Flow cytometry in combination with fluorescence probes was applied to rapidly assess the physiological status of Streptococcus macedonicus ACA-DC 198, a newly described member of the lactic acid bacteria group with technologically important features (e.g. lantibiotic production). A sonication procedure
M Renier et al.
Human gene therapy, 6(10), 1275-1283 (1995-10-01)
Cystic fibrosis is caused by defects in a chloride-transporting protein termed cystic fibrosis transmembrane conductance regulator (CFTR). This study presents an innovative procedure to evaluate expression of functional CFTR. The technique uses the potential-sensitive probe bis-(1,3-diethylthiobarbituric acid) trimethine oxonol or
L H Brent et al.
Journal of cellular physiology, 168(1), 155-165 (1996-07-01)
Myeloid cells, including granulocytes and monocyte/macrophages, are important in disease-associated inflammatory reactions. These cells come from a common progenitor, the promyelocyte. The human promyelocytic cell line, HL-60, can be induced to terminally differentiate into granulocytes or monocyte/ macrophages in a

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