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Merck

16702

Sigma-Aldrich

(R)-Pantethein

≥95.0% (HPLC)

Synonym(e):

(2R)-2,4-Dihydroxy-N-[3-[(2-mercaptoethyl)-amino]-3-oxopropyl]-3,3-dimethylbutanamid, (R)-2,4-Dihydroxy-N-[2-[(2-mercaptoethyl)-carbamoyl]-ethyl]-3,3-dimethylbutyramid, (D)-(+)-Pantethein, N-(Pantothenyl)-β-aminoethanthiol, LBF, Lactobacillus bulgaricus factor

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About This Item

Empirische Formel (Hill-System):
C11H22N2O4S
CAS-Nummer:
Molekulargewicht:
278.37
Beilstein:
1714196
MDL-Nummer:
UNSPSC-Code:
12352205
PubChem Substanz-ID:
NACRES:
NA.79

Qualitätsniveau

Assay

≥95.0% (HPLC)

Form

solid

Optische Aktivität

[α]/D 17±2°, c = 1 in H2O

Farbe

white

Lagertemp.

−20°C

SMILES String

OCC(C)(C)[C@@H](O)C(NCCC(NCCS)=O)=O

InChI

1S/C11H22N2O4S/c1-11(2,7-14)9(16)10(17)13-4-3-8(15)12-5-6-18/h9,14,16,18H,3-7H2,1-2H3,(H,12,15)(H,13,17)/t9-/m0/s1

InChIKey

ZNXZGRMVNNHPCA-VIFPVBQESA-N

Anwendung


  • Structures of carboxylic acid reductase reveal domain dynamics underlying catalysis: This study investigates the structural and dynamic aspects of carboxylic acid reductase enzymes, which are relevant for the conversion processes involving (R)-pantetheine and related compounds (Gahloth et al., 2017).

Biochem./physiol. Wirkung

Metabolite in carbapenem biosynthesis, pantothenate and CoA biosynthesis and biosynthesis of secondary metabolites.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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P Dykes et al.
Journal of wound care, 26(9), 552-557 (2017-09-08)
Preventing moisture damage and breakdown of the skin can be a particular challenge for patients with incontinence. The level of protection offered by various skin protectant products can vary according to the chemical nature of the formulation and can decrease
Lindsay E O'Donnell et al.
Journal of medical microbiology, 66(1), 54-60 (2016-12-30)
Approximately 20  % of the UK population wear some form of denture prosthesis, resulting in denture stomatitis in half of these individuals. Candida albicans is primarily attributed as the causative agent, due to its biofilm -forming ability. Recently, there has
Haeju Jo et al.
Materials (Basel, Switzerland), 13(18) (2020-09-25)
This study investigated the mechanical properties of steel in flanges, with the goal of obtaining high strength and high toughness. Quenching was applied alone or in combination with tempering at one of nine combinations of three temperatures TTEM and durations
H Kleinkauf et al.
Proceedings of the National Academy of Sciences of the United States of America, 68(9), 2069-2072 (1971-09-01)
To study the function of pantetheine in gramicidin S and tyrocidine biosynthesis, pepsin digests of the polymerizing enzymes, of which only the heavy ones contain pantetheine, were analyzed. The digests of gramicidin S enzymes charged with either [(14)C]proline or with
Patrice Brassard et al.
Critical care medicine, 44(4), 755-763 (2015-11-21)
Sympathetic vasoconstriction regulates peripheral circulation and controls blood pressure, but sepsis is associated with hypotension. We evaluated whether apparent loss of sympathetic vasoconstrictor responsiveness relates to distended smooth muscles or to endotoxemia and/or hypoxia. Prospective descriptive study. Hospital research laboratory.

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