Y0001177

Dexamethason für die Systemeignung

European Pharmacopoeia (EP) Reference Standard

• Synonym(e): Dexamethason, (11β,16α)-9-Fluor-11,17,21-trihydroxy-16-methylpregna-1,4-dien-3,20-dion, 9α-Fluor-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadien-3,20-dion, 9α-Fluor-16α-methylprednisolon, Prednisolon F
• Empirische Formel (Hill-System): C₂₂H₂₉FO₅
• CAS-Nummer: 50-02-2
• Molekulargewicht: 392.46
• Beilstein: 2066651
• MDL-Nummer: MFCD00064136
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329831293
• NACRES: NA.24

Eigenschaften

• Biologische Quelle: synthetic
• Qualität: pharmaceutical primary standard
• Agentur: EP
• API-Familie: dexamethasone
• Form: powder
• Verpackung: pkg of 10 mg
• Hersteller/Markenname: EDQM
• Lagerbedingungen: protect from light
• mp (Schmelzpunkt): 262-264 °C (lit.); 262-264 °C
• Löslichkeit: water: <0.1 g/L
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Versandbedingung: ambient
• Lagertemp.: 2-8°C
• SMILES String: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
• InChI: 1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
• InChIKey: UREBDLICKHMUKA-CXSFZGCWSA-N
• Angaben zum Gen: human ... NR3C1(2908)

Beschreibung

Allgemeine Beschreibung

Dexamethasone belongs to the class of synthetic glucocorticoid steroid drugs.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Dexamethasone is used as a pharmaceutical primary standard to quantify the analyte in pharmaceutical formulations using liquid chromatography (LC) technique.

Biochem./physiol. Wirkung

Glucocorticoid entzündungshemmendes Mittel. Reguliert T-Zell-Überleben, Wachstum und Differenzierung. Hemmt die Induktion von Stickstoffmonoxid-Synthase.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H360FD
• P-Sätze: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Gefahreneinstufungen: Repr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable