PHR1379

Atropinsulfat

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(e): Atropin -sulfat (Salz) Monohydrat, α-(Hydroxymethyl)-phenylessigsäure-8-methyl-8-azabicyclo[3.2.1]oct-3-ylester, (±)-Tropintropat
• Lineare Formel: (C₁₇H₂₃NO₃)₂ · H₂SO₄ · H₂O
• CAS-Nummer: 5908-99-6
• Molekulargewicht: 694.83
• Beilstein: 6109275
• EG-Nummer: 200-235-0
• MDL-Nummer: MFCD00074815
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329823356
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material; pharmaceutical secondary standard
• Qualitätsniveau: 300
• Agentur: traceable to BP 23; traceable to Ph. Eur. A1400000; traceable to USP 1045009
• API-Familie: atropine
• Analysenzertifikat (CofA): current certificate can be downloaded
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• mp (Schmelzpunkt): 189-192 °C (A) (lit.)
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: 2-8°C
• SMILES String: O.OS(O)(=O)=O.CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3.CN4[C@H]5CC[C@@H]4C[C@@H](C5)OC(=O)C(CO)c6ccccc6
• InChI: 1S/2C17H23NO3.H2O4S.H2O/c2*1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12;1-5(2,3)4;/h2*2-6,13-16,19H,7-11H2,1H3;(H2,1,2,3,4);1H2/t2*13-,14+,15+,16?;;
• InChIKey: JPKKQJKQTPNWTR-CHYDPLAESA-N
• Angaben zum Gen: human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131)

Beschreibung

Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Atropine Sulfate is an alkaloid extracted from belladonna herb. It is a cholinergic drug, administered as an anti-arrhythmic medicine.

Anwendung

Atropine Sulfate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by electrophoresis and chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem./physiol. Wirkung

Kompetitiver nichtselektiver Antagonist an zentralen und peripheren muskarinischen Acetylcholinrezeptoren.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAC4087 in the slot below. This is an example certificate only and may not be the lot that you receive.

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H300 + H330
• P-Sätze: P260 - P264 - P271 - P284 - P304 + P340 + P310 - P403 + P233
• Gefahreneinstufungen: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable