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Merck

M2649

Sigma-Aldrich

Melanin aus Sepia officinalis

99% purity (TLC), powder

Synonym(e):

Melanin

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

CAS-Nummer:
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12171500
NACRES:
NA.47

product name

Melanin aus Sepia officinalis, 99% (TLC)

Qualitätsniveau

Assay

99% (TLC)

Form

powder

Löslichkeit

hydrogen peroxide: 1 mg/mL, dark brown

Anwendung(en)

diagnostic assay manufacturing
hematology
histology

Lagertemp.

−20°C

InChI

1S/C18H10N2O4/c1-5-13-9-7(3-19-13)12-10-8(11(9)17(23)15(5)21)4-20-14(10)6(2)16(22)18(12)24/h3-4,19-20H,1-2H3

InChIKey

XUMBMVFBXHLACL-UHFFFAOYSA-N

Allgemeine Beschreibung

Melanin is a ubiquitous and prominent pigment responsible for color of skin, hair and eyes. Melanin is classified into eumelanin and pheomelanin. Eumelanin is black to dark brown pigment and is present in black hair and retina of the eye. Pheomelanin is yellow to reddish brown pigment present is red hair and red feathers. Melanins are high molecular weight pigments synthesized from phenolic or indolic precursors and is widely present in animals, plants and microorganisms.

Anwendung

Melanin from Sepia officinalis has been used:
  • as a natural pigment for Raman spectroscopy measurements
  • in competitive enzyme linked immunosorbent assay (ELISA) for the characterization of phage antibodies
  • as an external standard for spectrophotometrically determining the melanin production in B16F10 cells

Biochem./physiol. Wirkung

Melanin scavenges active chemical species and acts as a sunscreen.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Die Dokumentenbibliothek aufrufen

Localization of melanin in conidia of Alternaria alternata using phage display antibodies
Carzaniga R, et al.
Molecular plant-microbe interactions : MPMI, 15(3), 216-224 (2002)
Iwei Yeh et al.
Nature communications, 8(1), 644-644 (2017-09-25)
Deep penetrating nevus (DPN) is characterized by enlarged, pigmented melanocytes that extend through the dermis. DPN can be difficult to distinguish from melanoma but rarely displays aggressive biological behavior. Here, we identify a combination of mutations of the β-catenin and
Optical properties of melanin in the skin and skinlike phantoms.
Bashkatov AN
SPIE Proc. (2000)
Sunil Kalia et al.
Pigment cell & melanoma research, 31(1), 31-38 (2017-08-15)
Objective measurements of melanin can provide important information for differentiating melanoma from benign pigmented lesions and in assessing pigmentary diseases. Herein, we evaluate near-infrared (NIR) fluorescence as a possible tool to quantify melanin. Various concentrations of in vitro Sepia melanin
Influence of rosmarinic acid and Salvia officinalis extracts on melanogenesis of B16F10 cells
Oliveira KB, et al.
Revista Brasileira de Farmacognosia, 23(2), 249-258 (2013)

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