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Merck

I1892

Supelco

Ibuprofen Natriumsalz

≥98% (GC)

Synonym(e):

α-Methyl-4-(isobutyl)phenylacetic acid

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About This Item

Lineare Formel:
C13H17O2Na
CAS-Nummer:
Molekulargewicht:
228.26
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Assay

≥98% (GC)

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Löslichkeit

H2O: 100 mg/mL, clear to slightly hazy

Anwendung(en)

forensics and toxicology
pharmaceutical (small molecule)

Format

neat

SMILES String

[Na+].CC(C)Cc1ccc(cc1)C(C)C([O-])=O

InChI

1S/C13H18O2.Na/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15;/h4-7,9-10H,8H2,1-3H3,(H,14,15);/q;+1/p-1

InChIKey

PTTPUWGBPLLBKW-UHFFFAOYSA-M

Angaben zum Gen

Allgemeine Beschreibung

Ibuprofen belongs to the class of non-steroidal anti-inflammatory drugs, widely used for the treatment of mild to moderate pain and several forms of arthritis.

Anwendung

Ibuprofen sodium salt may be used as a model drug to study the intercalation mechanism via ion exchange reaction between ibuprofen and a biocompatible hydrotalcite compound.
Ibuprofen sodium salt may be used as an analytical reference standard for the qualification of the analyte in wastewaters using high-performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem./physiol. Wirkung

Inhibitor von Cyclooxygenase (COX), welcher eine höhere Aktivität gegen COX-1 als gegen COX-2 zeigt.

Empfohlene Produkte

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Kunden haben sich ebenfalls angesehen

Emanuele Mauri et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 146, 143-149 (2019-11-15)
Ibuprofen (IBU) is a non-steroidal anti-inflammatory drug (NSAID) commonly used in the treatment of pain, fever and inflammation. However, the administration of IBU in its free carboxylic acid form is strongly dependent on its limited solubility in aqueous solution. This
Determination of non-steroidal anti-inflammatory drugs in wastewaters by magnetic matrix solid phase dispersion?HPLC
Aguilar-Arteaga.K, et al.
Talanta, 80(3), 1152-1157 (2010)
Intercalation compounds of hydrotalcite-like anionic clays with antiinflammatory agents?I. Intercalation and in vitro release of ibuprofen
Ambrogi V, et al.
International Journal of Pharma Research & Review, 220, 23-32 (2001)
Fareeha Batool et al.
Materials (Basel, Switzerland), 11(4) (2018-04-13)
Ibuprofen (IBU) has been shown to improve periodontal treatment outcomes. The aim of this study was to develop a new anti-inflammatory scaffold by functionalizing an electrospun nanofibrous poly-ε-caprolactone membrane with IBU (IBU-PCL) and to evaluate its impact on periodontal inflammation
Abegaz Tizazu Andrgie et al.
Polymers, 12(11) (2020-11-12)
Hydrogels have been investigated as ideal biomaterials for wound treatment owing to their ability to form a highly moist environment which accelerates cell migration and tissue regeneration for prompt wound healing. They can also be used as a drug carrier

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