D1435

Dimethylsulfoxid

meets EP testing specifications, meets USP testing specifications

• Synonym(e): DMSO, Methylsulfoxid
• Lineare Formel: (CH₃)₂SO
• CAS-Nummer: 67-68-5
• Molekulargewicht: 78.13
• Beilstein: 506008
• EG-Nummer: 200-664-3
• MDL-Nummer: MFCD00002089
• UNSPSC-Code: 12191502
• PubChem Substanz-ID: 57654071
• NACRES: NA.71

Eigenschaften

• Agentur: meets EP testing specifications; meets USP testing specifications
• Qualitätsniveau: 200
• Dampfdichte: 2.7 (vs air)
• Dampfdruck: 0.42 mmHg ( 20 °C)
• Assay: ≥99.5%
• Form: liquid
• Selbstzündungstemp.: 573 °F
• Expl.-Gr.: 42 %, 63 °F
• Methode(n): cryopreservation: suitable
• Verunreinigungen: ≤0.1% water (Karl Fischer, USP); ≤0.2% water (Karl Fischer, EP)
• Farbe: colorless
• Brechungsindex: n20/D 1.478-1.479; n20/D 1.479 (lit.)
• bp: 189 °C (lit.)
• mp (Schmelzpunkt): 16-19 °C (lit.)
• Löslichkeit: H₂O: miscible (completely)
• Dichte: 1.100-1.104 g/mL at 25 °C (relative density (EP)); 1.10 g/mL (lit.)
• UV-Absorption: λ: 285 nm A_max: ≤0.20; λ: 295 nm A_max: ≤0.20
• SMILES String: CS(C)=O
• InChI: 1S/C2H6OS/c1-4(2)3/h1-2H3
• InChIKey: IAZDPXIOMUYVGZ-UHFFFAOYSA-N

Beschreibung

Anwendung

Dimethyl sulfoxide has been used:

• for the dissolution of tetramethylrhodamine dye, which is used as fluorophore for fluorescence in- situ hybridization (FISH) experiments
• as a control in indirect immunofluorescent assay (IFA) of swine testicular (ST) cells
• for the suspension and separation of buccal cells
• a polar aprotic solvent used in polymerase chain reactions (PCR) and as a cryoprotectant vitrification agent for the preservation of cells, tissues and organs.

Biochem./physiol. Wirkung

Dimethyl sulfoxide (DMSO) is a low molecular weight, less hydrophilic and a freely permeable cryoprotectant. It is a polar aprotic solvent used in polymerase chain reactions (PCR) and as a cryoprotectant and vitrification agent for the preservation of cells, tissues and organs.

Vorsicht

Unterkühlt leicht und schmilzt langsam bei Raumtemperatur. Das verfestigte Produkt kann durch Erwärmen auf Raumtemperatur wieder verflüssigt werden, ohne dabei geschädigt zu werden.

Sonstige Hinweise

For information on dimethyl sulfoxide miscibility, please visit the following link:
Dimethyl Sulfoxide Miscibility/Immiscibility Table

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): 188.6 °F - closed cup
• Flammpunkt (°C): 87 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type ABEK (EN14387) respirator filter