91275

Propionyl-L-carnitin

analytical standard

• Synonym(e): (2R)-3-Carboxy-N,N,N-trimethyl-2-(1-oxopropoxy)-1-propanaminium Inneres Salz, L-Carnitin-propionylester, C3-Carnitin, Propanoyl-L-carnitin
• Empirische Formel (Hill-System): C₁₀H₁₉NO₄
• CAS-Nummer: 20064-19-1
• Molekulargewicht: 217.26
• MDL-Nummer: MFCD00870024
• UNSPSC-Code: 41116107
• NACRES: NB.21

Eigenschaften

• Qualität: analytical standard
• Qualitätsniveau: 100
• Assay: ≥94.0% (HPLC)
• Optische Aktivität: [α]/D -24.0±2.0°, c = 0.2 in H₂O
• Haltbarkeit: limited shelf life, expiry date on the label
• Verunreinigungen: ≤13% water ((calculated from elemental analysis)
• Anwendung(en): clinical testing
• Format: neat
• Lagertemp.: 2-8°C
• SMILES String: [O-]C(C[C@@H](OC(CC)=O)C[N+](C)(C)C)=O
• InChI: 1S/C10H19NO4/c1-5-10(14)15-8(6-9(12)13)7-11(2,3)4/h8H,5-7H2,1-4H3/t8-/m1/s1
• InChIKey: UFAHZIUFPNSHSL-MRVPVSSYSA-N

Beschreibung

Allgemeine Beschreibung

Propionyl-L-carnitine (PLC), a natural odd-carbon-number, endogenous ester of L-carnitine, is found to be present in humans and animals as a minor component compared to L-carnitine (LC) and acetyl-L-carnitine (ALC). It acts as a carrier of long chain acyl groups from activated fatty acids across the inner mitochondrial membrane into the mitochondrial matrix where they undergo β-oxidation to acetyl CoA to obtain usable energy via the citric acid cycle.

Anwendung

Propionyl-L-carnitine may be used as an analytical reference standard for the quantification of the analyte in biological samples using chromatography-based techniques. It may also be used as an analytical standard in monitoring the analyte in chemical synthesis procedures and pharmaceutical formulations using a stereospecific enzyme assay and high-performance liquid chromatography technique with UV detection.

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Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable