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Merck

49777

Supelco

Neotam

analytical standard

Synonym(e):

N-[N-(3,3-Dimethylbutyl)-L-α-aspartyl]-L-phenylalanin-1-methylester

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About This Item

Empirische Formel (Hill-System):
C20H30N2O5
CAS-Nummer:
Molekulargewicht:
378.46
Beilstein:
8352678
MDL-Nummer:
UNSPSC-Code:
85151701
PubChem Substanz-ID:
E-Nummer:
E961
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Assay

≥98.0% (HPLC)

Optische Aktivität

[α]/D -41.0±3.0°, c = 0.5 in H2O

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

cleaning products
cosmetics
food and beverages
personal care

Format

neat

SMILES String

COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NCCC(C)(C)C

InChI

1S/C20H30N2O5/c1-20(2,3)10-11-21-15(13-17(23)24)18(25)22-16(19(26)27-4)12-14-8-6-5-7-9-14/h5-9,15-16,21H,10-13H2,1-4H3,(H,22,25)(H,23,24)/t15-,16-/m0/s1

InChIKey

HLIAVLHNDJUHFG-HOTGVXAUSA-N

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Allgemeine Beschreibung

Neotame is a white colored, dipeptide methyl ester, which is found to be a highly potent and non-nutritive sweetener or flavour enhancer and hence finds applications in variety of foods. It is manufactured from aspartame and 3,3-dimethylbutyraldehyde in a one-step chemical synthesis process.
Neotame is chemically related to aspartame, an artificial sweetener, used in the production of sugar-free low-calorie foodstuffs. It is approved as a food additive depending upon the food or beverage application.

Anwendung

Neotame may be used as an analytical reference standard for the quantification of the analyte in the following:
  • Wine samples using reversed-phase high-performance liquid chromatography (RP-HPLC).
  • Wastewaters using hydrophilic interaction liquid chromatography (HILIC).
  • Food samples using high-performance liquid chromatography (HPLC).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Analysenzertifikate (COA)

Lot/Batch Number

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Joint RAO/WHO Expert Committee on Food Additives, World Health Organization
Evaluation of Certain Food Additives: Seventy-first Report of the Joint FAO/WHO Expert Committee on Food Additives (2004)
Determination of nine high-intensity sweeteners in various foods by high-performance liquid chromatography with mass spectrometric detection
Zygler A, et al.
Analytical and Bioanalytical Chemistry, 400(07), 2159-2172 (2011)
Neotame: discovery, properties, utility
Nofre C and Tinti M-J
Food Chemistry, 69, 245-257 (2000)
Modifying the temporal profile of the high-potency sweetener neotame
Prakash I, et al.
Journal of Agricultural and Food Chemistry, 49, 786-789 (2001)
Determination of eight artificial sweeteners in wastewater by hydrophilic interaction liquid chromatography-tandem mass spectrometry
Kokotou GM and Thomaidis SN
Analytical Methods : Advancing Methods and Applications, 5(16), 3825-3833 (2013)

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