31742

Levamisol -hydrochlorid

VETRANAL^®, analytical standard

• Synonym(e): (−)-Tetramisol -hydrochlorid, (S)-(−)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazol -hydrochlorid, L(−)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazol -hydrochlorid, Levamisol -hydrochlorid
• Empirische Formel (Hill-System): C₁₁H₁₂N₂S · HCl
• CAS-Nummer: 16595-80-5
• Molekulargewicht: 240.75
• Beilstein: 4358988
• EG-Nummer: 240-654-6
• MDL-Nummer: MFCD00012675
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329753914
• NACRES: NA.24

Eigenschaften

• Qualität: analytical standard
• Qualitätsniveau: 100
• Produktlinie: VETRANAL^®
• Haltbarkeit: limited shelf life, expiry date on the label
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• mp (Schmelzpunkt): 228-230 °C
• Anwendung(en): forensics and toxicology; pharmaceutical (small molecule)
• Format: neat
• SMILES String: Cl.C1CN2C[C@@H](N=C2S1)c3ccccc3
• InChI: 1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H/t10-;/m1./s1
• InChIKey: LAZPBGZRMVRFKY-HNCPQSOCSA-N

Beschreibung

Allgemeine Beschreibung

Levamisol hydrochloride is an anthelmintic drug which possesses immunomodulatory and anticancer properties. It is a white crystalline compound which is stable in acid aqueous media, whereas it hydrolyzes in alkaline/neutral solutions.

Anwendung

Levamisol hydrochloride may have been used as antibiotic standard in ultra-high-pressure liquid chromatography–tandem mass spectrometry for determination of veterinary drug residues from milk samples.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem./physiol. Wirkung

Zeigt sowohl immunstimulierende als auch immunsuppressive Wirkungen, abhängig von verschiedenen steuerbaren Faktoren. Sehr wirksam bei der Behandlung von Ascariasis (Hakenwürmer Befall). Nützlich in der Chemotherapie von kolorektalen Karzinomen, möglicherweise aufgrund seiner Stimulation der IL-1 Produktion und direkter Aktivierung von Makrophagen.

Empfohlene Produkte

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Rechtliche Hinweise

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H301
• P-Sätze: P264 - P270 - P301 + P310 - P405 - P501
• Gefahreneinstufungen: Acute Tox. 3 Oral
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges