SCC249
Hep-G2/2.2.15 Human Hepatoblastoma Cell Line
The Hep-G2/2.2.15 human hepatoblastoma cell line is a suitable model for research into many aspects of HBV-associated liver cancer.
Synonym(e):
Hep-G2/2215
About This Item
Empfohlene Produkte
Anwendung(en)
cell analysis
Allgemeine Beschreibung
The Hep-G2/2.2.15 human hepatoblastoma cell line, a subclone of HepG2 human hepatoblastoma that stably expresses the hepatitis B virus, is one of the most widely used models for HBV-associated liver disease. Hep-G2/2.2.15 cells possess lower proliferation and invasion activity than parental HepG2 cells and have low tumorigenicity in nude mice (2). Like parental HepG2 cells, Hep-G2/2.2.15 cells express the microtubule-associated marker doublecortin (DCX).
<bold>Source:</bold>
Hep-G2/2.2.15 was produced from Hep-G2 cells stably transformed with the hepatitis-B virus (HBV) genome. Hep-G2/2.2.15 cells are resistant to G418 and contain two head-to-tail dimers of the HBV type D genome (3). The parental HepG2 cell line was isolated from hepatoblastoma tissue of a 15-year-old male patient (4).
Research Category:
- Cancer
- Infectious Diseases
Ursprung der Zelllinie
Verpackung
Lagerung und Haltbarkeit
Sonstige Hinweise
Haftungsausschluss
Within the EU GMOs are regulated by Directives 2001/18/EC and 2009/41/EC of the European Parliament and of the Council and their national implementation in the member States respectively. Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Lagerklassenschlüssel
12 - Non Combustible Liquids
WGK
WGK 1
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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