Direkt zum Inhalt
Merck
Alle Fotos(1)

Wichtige Dokumente

MAB390-100UG

Sigma-Aldrich

Anti-p75 LNGFR Antibody, Saporin conjugated, clone 192

clone 192, Chemicon®, from mouse

Synonym(e):

p75 Low Affinity Neurotrophin Receptor, NGFR

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

Konjugat

saporin

Antikörper-Produkttyp

primary antibodies

Klon

192, monoclonal

Speziesreaktivität

rat

Darf nicht reagieren mit

mouse, human

Hersteller/Markenname

Chemicon®

Methode(n)

immunolesioning: suitable

Isotyp

IgG1

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... NGFR(4804)

Spezifität

Rat NGF receptor. MAB365 is the monoclonal antibody used for MAB390-SAP

Anwendung

Research Category
Neurowissenschaft
Research Sub Category
Neurodegenerative Krankheiten

Neurochemie & Neurotrophine
Anti-p75 Low Affinity Nerve Growth Factor Receptor Antibody, Saporin conjugated, clone 192 is an antibody against p75 Low Affinity Nerve Growth Factor Receptor for use in 0.
Immunotoxin (see "Protocols" for Technical Notes)

Physikalische Form

Saporin Conjugated. 192-IgG-SAP is sterile filtered and presented in Dulbecco′s PBS with no preservative.

Lagerung und Haltbarkeit

Centrifuge material at low speed in microfuge to ensure all of the solution is at the bottom of the tube. Vortex gently. Long term storage at -70ºC or below. Short term storage at -20ºC or 2-8ºC with appropriate antibacterial agent if compatible with the intended application. The sterile conjugate is stable at 2-8ºC for several months. Avoid repeated freezing and thawing. Glycerol (1:1) can be added for additional stability if compatible with the intended application. This immunotoxin may be handled safely using standard laboratory procedures as the cross-species reactivity between these anti-rat p75 antibodies and the human form of p75 is negligible.

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sie haben nicht das passende Produkt gefunden?  

Probieren Sie unser Produkt-Auswahlhilfe. aus.


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

S Rossner et al.
Journal of neuroscience research, 38(3), 282-293 (1994-06-15)
The aim of this study was to show whether reduction or loss of cortical cholinergic activity results in any particular change in the expression of the proto-oncogenes c-fos and/or c-jun. To produce cortical cholinergic hypofunction, the monoclonal antibody, 192IgG, to
Neural lesioning with ribosome-inactivating proteins: suicide transport and immunolesioning.
Wiley, R G
Trends in Neurosciences, 15, 285-290 (1992)
M Gallagher et al.
Current opinion in neurobiology, 5(2), 161-168 (1995-04-01)
The concept that memory loss in ageing might be attributable to deficiencies in cholinergic function was first proposed two decades ago. This proposal gained additional definition when pathology was found in the basal forebrain cholinergic system of patients with Alzheimer's
Selective lesioning of the basal forebrain cholinergic system by intraventricular 192 IgG-saporin: behavioural, biochemical and stereological studies in the rat.
Leanza, G, et al.
The European Journal of Neuroscience, 7, 329-343 (1995)
Removal of cholinergic input to rat posterior parietal cortex disrupts incremental processing of conditioned stimuli.
Bucci, D J, et al.
The Journal of Neuroscience, 18, 8038-8046 (1998)

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.