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DR1071

Sigma-Aldrich

Anti-TFAM Rabbit pAb

liquid, Calbiochem®

Synonym(e):

Anti-Transcription Factor A Mitochondrial

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Antikörperform

purified antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

liquid

Enthält nicht

preservative

Speziesreaktivität

mouse, human

Hersteller/Markenname

Calbiochem®

Lagerbedingungen

OK to freeze
avoid repeated freeze/thaw cycles

Isotyp

IgG

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... TFAM(7019)

Allgemeine Beschreibung

Purified rabbit polyclonal antibody. Recognizes the ~30 kDa TFAM protein.
Recognizes the ~30 kDa TFAM protein in mouse liver tissue.
This Anti-TFAM Rabbit pAb is validated for use in Immunoblotting for the detection of TFAM.

Immunogen

Full-length, human TFAM (aa 1-246)
Human

Anwendung


Immunoblotting (1-5 g/ml)

Warnhinweis

Toxicity: Regulatory Review (Z)

Physikalische Form

In PBS, pH 7.13.

Rekonstituierung

Following initial thaw, aliquot and freeze (-20°C).

Hinweis zur Analyse

Negative Control
293T cells
Positive Control
Mouse liver tissue

Sonstige Hinweise

Variables associated with assay conditions will dictate the proper working dilution.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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J Matthew Hinkley et al.
Medicine and science in sports and exercise, 51(6), 1106-1115 (2019-01-11)
Doxorubicin (DOX) is a highly effective chemotherapeutic agent used in the treatment of a broad spectrum of cancers. However, clinical use of DOX is limited by irreversible and dose-dependent hepatotoxicity. The liver is the primary organ responsible for the clearance
Pieter A Leermakers et al.
BMC pulmonary medicine, 20(1), 20-20 (2020-01-23)
Both mitophagy, a selective mechanism for clearance of mitochondria, and mitochondrial biogenesis are key processes determining mitochondrial content and oxidative capacity of the musculature. Abnormalities in these processes could therefore contribute to deterioration of peripheral muscle oxidative capacity as observed
Wessel F Theeuwes et al.
Biochimica et biophysica acta. Molecular basis of disease, 1866(6), 165740-165740 (2020-02-23)
Physical inactivity contributes to muscle wasting and reductions in mitochondrial oxidative phenotype (OXPHEN), reducing physical performance and quality of life during aging and in chronic disease. Previously, it was shown that inactivation of glycogen synthase kinase (GSK)-3β stimulates muscle protein
Rosario Barone et al.
Journal of cellular physiology, 232(5), 1086-1094 (2016-08-04)
Conjugated linoleic acid (CLA) has been reported to improve muscle hypertrophy, steroidogenesis, physical activity, and endurance capacity in mice, although the molecular mechanisms of its actions are not completely understood. The aim of the present study was to identify whether
Philippe Vangrieken et al.
PloS one, 16(1), e0245155-e0245155 (2021-01-13)
Impaired utero-placental perfusion is a well-known feature of early preeclampsia and is associated with placental hypoxia and oxidative stress. Although aberrations at the level of the mitochondrion have been implicated in PE pathophysiology, whether or not hypoxia-induced mitochondrial abnormalities contribute

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