AB3841

Anti-Connexin 43 Antibody, phospho-specific (Ser368)

Chemicon^®, from rabbit

• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Aufgereinigt durch: affinity chromatography
• Speziesreaktivität: hamster, mouse, rat, monkey, human
• Hersteller/Markenname: Chemicon^®
• Methode(n): western blot: suitable
• NCBI-Hinterlegungsnummer: NM_000165.3
• UniProt-Hinterlegungsnummer: P17302
• Versandbedingung: dry ice
• Posttranslationale Modifikation Target: phosphorylation (pSer368)
• Angaben zum Gen: human ... GJA1(2697)

Beschreibung

Spezifität

Recognizes Ser368 phosphorylated Connexin 43. Connexin 43 (Cx43) is a member of the large family of gap junction proteins. Connexins assemble as a hexamer and are transported to the plasma membrane to create a hemichannel that can associate with hemichannels on nearby cells to create cell-to-cell channels. Clusters of these channels assemble to make gap junctions. Gap-junction communication is important in development and regulation of cell growth.

Immunogen

Epitope: phospho-specific (Ser368)

KLH-conjugated, synthetic phospho-peptide corresponding to residues surrounding Ser368 of human Connexin 43.

Anwendung

Research Category
Zellstruktur

Research Sub Category
Adhäsions-Proteine (CAMs – Zelladhäsionsmoleküle)

This Anti-Connexin 43 Antibody, phospho-specific (Ser368) is validated for use in WB for the detection of Connexin 43.

Western blotting 1:1,000 (for best results, incubate membrane with diluted antibody in 5% BSA, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight)

Optimal working dilutions must be determined by the end user.

Physikalische Form

Protein A and peptide affinity purified immunoglobulin. Liquid in 10 mM sodium HEPES, pH 7.5, 150 mM NaCl, 100 μg/mL BSA, with 50% glycerol.

Lagerung und Haltbarkeit

Maintain at -20ºC for 12 months after date of receipt. Do not aliquot.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 2