8.55049

H-Thr-Gly-NovaSyn^® TG resin

Novabiochem^®

• UNSPSC-Code: 13111023
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 200
• Produktlinie: NovaSyn^® TG; Novabiochem^®
• Form: beads
• Eignung der Reaktion: reaction type: Fmoc solid-phase peptide synthesis; reactivity: carbonyl reactive
• Hersteller/Markenname: Novabiochem^®
• Anwendung(en): peptide synthesis
• Funktionelle Gruppe: amine
• Lagertemp.: 2-8°C

Beschreibung

Allgemeine Beschreibung

This resin is a useful tool for the synthesis of peptide aldehydes^[1]. Attachment of pre-formed amino acid aldehydes to this resin is effected by heating in 1% DIPEA in MeOH at 60 °C. Following chain extension using standard protocols, side-chain protecting groups can be removed with anhydrous TFA, prior to cleavage of the fully deprotected peptide aldehyde with MeCN/water/TFA. An analogous resin has been recently used to capture and purify peptide aldehydes generated by oxidation of peptide alcohols with IBX-polystyrene ^[2]. Novabiochem′s pre-loaded amino aldehyde resins can be found on page x.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Verlinkung

Replaces: 04-12-3710

Hinweis zur Analyse

Farbe (visuell): weiß bis gelb bis beige
Aussehen der Substanz (visuell): Kügelchen
Beladung (Photometrische Bestimmung des Fmoc-Chromophores nach Abspaltung vom Fmoc-Oxybenzaldehyd beladenen Harz.): 0.15 - 0.35 mmol/g
Identität (der Beladung): entspricht
Aufquellvolumen (in DMF): chargenspezifischer Wert
Das Basisharz ist Amino-PEG-PS-Copolymerisat (90 µm)

Rechtliche Hinweise

NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable