444244

MMP-2 Inhibitor I

The MMP-2 Inhibitor I, also referenced under CAS 10335-69-0, controls the biological activity of MMP-2. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

• Synonym(e): MMP-2 Inhibitor I, cis-9-Octadecenoyl-N-hydroxylamide, Oleoyl-N-hydroxylamide, OA-Hy
• Empirische Formel (Hill-System): C₁₈H₃₅NO₂
• CAS-Nummer: 10335-69-0
• Molekulargewicht: 297.48
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: solid
• Wirksamkeit: 1.7 mM K_i
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; protect from light
• Farbe: white
• Löslichkeit: DMSO: 2 mg/mL; ethanol: 3 mg/mL
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• InChI: 1S/C18H35NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(20)19-21/h9-10,21H,2-8,11-17H2,1H3,(H,19,20)/b10-9-
• InChIKey: LTXHELLMCCEDJG-KTKRTIGZSA-N

Beschreibung

Allgemeine Beschreibung

A cell-permeable, potent inhibitor of MMP-2 that acts in a dose-dependent manner (K_i = 1.7 µM).

Potent inhibitor of MMP-2 (gelatinase A). Inhibits MMP-2 in a dose dependent manner (K_i = 1.7 µM)

Biochem./physiol. Wirkung

Cell permeable: yes

Primary Target
MMP-2

Product does not compete with ATP.

Reversible: no

Verpackung

Packaged under inert gas

Warnhinweis

Toxicity: Standard Handling (A)

Rekonstituierung

Unstable in solution; reconstitute just prior to use.

Sonstige Hinweise

Berton, A., et. al. 2001. J. Biol. Chem.276, 20458.
Emonard, H., et al. 1999. Ann. N.Y. Acad. Sci.878, 647.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable