QBD10198

NHS-dPEG^®₁₂-biotin

• Synonym(e): NHS-PEG Linker, Polyethylene glycol
• Empirische Formel (Hill-System): C₄₁H₇₂N₄O₁₈S
• Molekulargewicht: 941.09
• UNSPSC-Code: 12161502
• PubChem Substanz-ID: 329823889
• NACRES: NA.22

Eigenschaften

• Assay: >90%
• Form: solid or viscous liquid
• Eignung der Reaktion: reagent type: cross-linking reagent; reaction type: Biotinylations; reactivity: amine reactive
• Polymerarchitektur: shape: linear; functionality: monofunctional
• Versandbedingung: ambient
• Lagertemp.: −20°C
• SMILES String: O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCCC1C2NC(NC2CS1)=O)=O)ON3C(CCC3=O)=O

Beschreibung

Leistungsmerkmale und Vorteile

NHS-dPEG^®₁₂-biotin is used extensively to label molecules that contain a free amine with biotin. The single molecular weight NHS-dPEG^®₁₂-biotin has a long spacer of precise length (47.6 Å) between the biotin moiety and the labeled molecule. This dPEG^® spacer imparts a high degree of water solubility to the biotin label. For biotinylated peptides and proteins, the dPEG^® spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin.

Rechtliche Hinweise

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable